Blood bank immunohematology Review Questions with complete Solutions Graded A+
1 view 0 purchase
Course
Blood Bank
Institution
Blood Bank
Blood bank immunohematology Review Questions with complete Solutions Graded A+
The loss of ATP leads to - Answers A decrease in phosphorylation of spectrin and loss of membrane deformability
The majority of normal adult hemoglobin consists of - Answers 2 alpha chains and 2 beta chains
When RBC's...
Blood bank immunohematology Review Questions with complete Solutions Graded A+
The loss of ATP leads to - Answers A decrease in phosphorylation of spectrin and loss of membrane
deformability
The majority of normal adult hemoglobin consists of - Answers 2 alpha chains and 2 beta chains
When RBC's are stored, there is a "shift to the left" which means - Answers Hemoglobin oxygen affinity
increases, owing to a decrease in 2,3-DPG.
What is the role of platelets (3 things) - Answers Maintain vascular integrity
initial arrest of bleeding
stabilizing of hemostatic plug
What anticoagulant-preservatives provide a storage time of 21 days at 1-6degreesC for whole blood and
prepared RBC's if an additive solution is not added? - Answers ACD
CP2D
CPD
What is current storage time and temp for platelet concentrates and apheresis platelet components? -
Answers 5 days at 20-24 degrees C
What is the minimum number of platelets required in a platelet concentrate prepared from whole blood
by centrifugation (90% of sampled units)? - Answers 5.5 x 10^11
What factors will influence platelet metabolism and viability in a closed container system? - Answers
Total platelet count,
duration of storage,
temperature of storage.
NOT fibrinogen concentration
What is the minimum number of platelets required in an apheresis component (90% of sampled units)? -
Answers 3 x 10^11
Whole blood and RBC units are stored at what temperature? - Answers 1-6degrees C
Additive solutions are approved for blood storage for how many days? - Answers 42
Whole blood/RBC's can be stored in CPDA-1 at 1-6degrees for how many days? - Answers 35
What is the lowest allowable pH for a platelet component at outdate? - Answers 6.2
,Frozen/thawed RBC's processed in an open system can be stored for how long? - Answers 24 hours
What is the hemoglobin source for hemoglobin-based RBC substitutes in advanced clinical testing. -
Answers Both bovine and human hemoglobins.
Meiosis - Answers Genetic material is duplicated, equally divided between 2 daughter cells.
When a recessive trait is expressed, it means that - Answers Two genes carrying the trait were present.
In a pedigree, the "index case" is another name for - Answers Propositus
What 4 nitrogenous bases make up DNA? - Answers Adenine, cytosine, guanine, thymine.
Proteins and peptides are composed of - Answers linear arrangements of amino acids.
Which phenotype could not result from the mating of a
Jk(a+b+) female and a Jk(a+b+) male - Answers Jk(a-b-)
Exon - Answers The coding region of a gene.
PCR technology can be used to - Answers amplify small amounts of DNA.
Transcription - Answers Synthesis of RNA using DNA as a template.
When a man possesses a phenotypic trait he passes it to all his daughters and none of his sons, the trait
is: - Answers X-linked dominant
When a woman possesses a phenotypic trait that she passes to all of her sons and none of her
daughters, it is - Answers X-linked recessive
DNA is replicated - Answers Semiconservatively from DNA
RNA is processed - Answers After RNA is copied from DNA
Translation of proteins from RNA takes place - Answers Inside the nucleolus of the cell
Meiosis is necessary to - Answers generate new DNA sequences in daughter cells.
Characteristic of the acquired IS include - Answers production of antibody and lymphokines
Substances that participate in the regulation of the immune response. - Answers Cytokines
What cell is identified primarily by the presence of immunoglobulin on its surface? - Answers B cell
Which cell functions primarily in antigen processing and presentation? - Answers Macrophage
Which is the signal for the expression of IL-2 receptors on a TH cell? - Answers Presentation of antigen
by a monocyte to a TH cell.
, Which class of HLA markers are important in immune recognition of antigen in cell-to-cell interactions? -
Answers Class II
Which immunoglobulin class would be most important in the study of immune-mediated transfusion
reactions due to the presence of alloantibodies? - Answers IgG
Which immunoglobulins can activate the classic pathway of the complement system? - Answers IgG1,
IgG3, IgM
Which complement factor is common to both classic and alternative pathways and will result in the
formation of MAC? - Answers Factor C3
Which of the following patient samples for blood bank testing is most likely to contain active
complement?
*EDTA sample
*Heparin sample
*Serum sample drawn 2 days ago
*Serum sample drawn 2 hours ago - Answers Serum sample drawn 2 hours ago
Which one of the following statements is true concerning the formation of antibodies to blood group
antigens?
*All blood group antigens are immunogenic
*Only ABO and Rh group antigens are immunogenic
*Antibodies may form against any foreign blood group antigen
*Antibodies formed against Kidd antigens are always IgM - Answers Antibodies may form against any
foreign blood group antigen
Antibody idiotype is determined by the - Answers Variable regions of heavy and light chains.
What antibody is produced rapidly and in the highest amounts during secondary response? - Answers
IgG
Which of the following is mostly likely to account for the Failure of a visible RBC antigen-antibody
reaction?
*Homozygous expression of an antigen on an RBC
*pH of 7.2
*Incubation at 37degrees for suspended IgG antibody
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller TutorJosh. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $8.99. You're not tied to anything after your purchase.
