What are the clinical features of a child with Down
Syndrome? Correct Answer epicanthal folds
slanted eyes
flat facial profile
malformed ears
congenital heart disease
acute lymphoblastic leukemia
growth failure
flat occiput
big, protruding, wrinkled tongue
intestinal malformations
short, broad hands with simian crease
wide gab between first and second toes
What is a numeric disorder involving autosomal
chromosomes? Correct Answer Down Syndrome
What is another name for Down Syndrome? Correct
Answer Trisomy 21
What are the clinical features of Turner Syndrome?
Correct Answer small stature
broad chest with widely spaced nipples
poor breast development
,ovarian dysgenesis with primary amenorrhea, estrogen
and progesterone deficiencies
infertility
multiple pigmented nevi
lymphedema of hands and feet
low posterior hairline
webbed neck
coarctation of aorta and bicuspid aortic valve
wide carrying angle of arms
retardation of bone age
What is the most prominent clinical feature of Turner
Syndrome? Correct Answer absent/nonfunctioning ovaries
(causing a lack of secondary female sexual
characteristics)
What is a numeric disorder involving sex chromosomes?
Correct Answer Turner Syndrome
What are FASDs? Correct Answer a group of conditions
that can occur in a person whose mother drank alcohol
during pregnancy
mother drank alcohol during pregnancy causing physical
problems and problems with behavior and learning in her
child Correct Answer Fetal Alcohol Spectrum Disorders
Is there a safe amount to drink when pregnant or trying to
get pregnant? Correct Answer no (a woman may not know
she's pregnant for up to 4-6 weeks, 50% of US
pregnancies are unplanned)
, What genetic disorders are we required to know for this
class? Correct Answer Marfan Syndrome
Phenylketonuria (PKU)
Fragile X Syndrome (FXS)
Down Syndrome
Turner Syndrome
Fetal Alcohol Spectrum Disorders (FASDs)
The longer the life expectancy of the cell, the ___ the
mitotic rate. Correct Answer slower
What does abnormal cell division produce? Correct
Answer tumors (neoplasms)
What are the two types of neoplasms? Correct Answer
benign
malignant
composed of well-differentiated cells
resemble tissue of origin
slow, progressive rate of growth
expand at site of origin
develop a capsule = do not invade surrounding tissue
Correct Answer benign neoplasm
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