Class notes
6. Genetics and Pedigrees
- Course
- Institution
Genetics and Pedigrees topic from Biology 1B
[Show more]
Seller
Follow
BiologyStudent
Reviews received
Content preview
Genetic and Cellular Principles – Model organisms & General principles ofDevelopment
Define the terms: determination, differentiation, and morphogenesis
Determination - The commitment of a cell to a particular path of differentiation, even though there
may be no morphological features that reveal this determination.
Differentiation - The normal process by which a less specialized cell develops or matures to become
more distinct in form and function
Morphogenesis - The development of form; the overall consequence
of determination, differentiation, and growth.
Understand that genes control the detailed process of development, but to do so they must
be responsive to signals from outside the cells
In the previous notes (Mammalian development)
Understand how model organisms such as the fruit fly Drosophila melanogaster have played
a critical role in our current understanding of the molecular principles of development
• The Homeotic genes specify regional identity to body segments. They define what structures
are produced by a particular segment.
• The Homeotic genes encode transcription factors.
• Homeotic genes all contain a conserved “Homeobox” DNA motif (Hox). A cluster of related
homeotic genes – the Hox gene cluster(s).
• Encodes a DNA binding domain in proteins.
• HOX genes encode transcription factors - regulate expression of other genes.
• Expression of HOX proteins is a Global Positioning System giving Regional Identity in animals.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller BiologyStudent. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.09. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
53068 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now