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Exam (elaborations)

CDCES Questions and Answers 2024/2025

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Fiasp (insulin aspart)  Onset 2.5 min; peak 60 min; lasts 3-5 hr Aspart (Novolog); lispro (humalog); glulisine (apidra)  Onset 5-15 min; peak 30-90 min; lasts <5 hrs Regular insulin bolus  Onset 30-60 min; peak 2-3 hrs; lasts 5-8 hrs NPH insulin  Onset 2-4 hrs; peak 4-10 hrs; ...

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  • October 10, 2024
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  • CDCES
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2 0 2 4 /2025 | © copyright | This work may not be copied for profit gain Excel!

CDCES


CDCES Questions and Answers
2024/2025
Fiasp (insulin aspart)

 Onset 2.5 min; peak 60 min; lasts 3-5 hr


Aspart (Novolog); lispro (humalog); glulisine (apidra)


 Onset 5-15 min; peak 30-90 min; lasts <5 hrs


Regular insulin bolus

 Onset 30-60 min; peak 2-3 hrs; lasts 5-8 hrs


NPH insulin

 Onset 2-4 hrs; peak 4-10 hrs; lasts 10-16 hrs


Detemir (Levemir)

 Onset 3-8 hrs; no peak; lasts 6-24 hrs


Glargine (Lantus/basaglar)

 Onset 2-4 hrs; no peak; lasts 20-24 hrs


Degludec (Tresiba)

 Onset 1 hr; no peak; lasts <42 hrs


NPH mix with reg (70/3" or 50/50)

1|Page| GradeA+ | 2 0 0 2 5

, 2 0 2 4 /2025 | © copyright | This work may not be copied for profit gain Excel!

 Onset 30-60 min; dual peak; lasts 10-16 hrs


Novolog/humalog or ryzodeg mix (70/30, (75/25, 50/50)


 Onset 5-15 min; dual peak; lasts 24 hrs


GLP-1 receptor agonists action

 Incretin mimetic; increases insulin release with good, slows gastric emptying, promote
satiety, suppresses glucagon; reduces risk of cv death, MI, and stroke ; lowers A1C .5-
1.6, 1.6-6 kg weight loss


GLP-1 agonists names


 Exabatide (byetta), exanitide xr (bydureon), lieaglutide (Victoza), dulaglutide
(trulicity), lixisenatide (adlyxin), semaglutide (ozempic), rybelsus


GLP-1 agonists side effects

 Nausea, vomiting, weight loss, injection site reaction, pancreatitis (abd pain, vomiting);
avoid liraglutide, dulaglutide, and semaglutide if fam hx of thyroid tumor


Amylin Mimetics (pramlintide/Symlin)

 Slows gastric emptying, suppressed glucagon; side effects - severe hypoglycemia risk,
decrease insulin when starting, nausea, weight loss (lowers A1C .5-1)


Ideglira (xultophy)


 Combines degludec (ideg or tresiba) + liraglutide (victoza); daily injection 10-50
units, start at 16 and titrate by 2 units


Iglarlixi (soliqua)




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