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Schema galexcretie
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GalexcretieFagocytose rode bloedcellen
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In fagocyt wordt haem-ring omgezet tot ongeconjugeerd bilirubine
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Ongeconjugeerd bilirubine komt vrij in plasma
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Ongeconjugeerd bilirubine bindt zich met albumine
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Ongeconjugeerd bilirubine wordt ontdaan van albumine en gaat binnen in hepatocyt
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Ongeconjugeerd bilirubine wordt gekoppeld aan glucuronzuur en er ontstaat geconjugeerd bilirubine
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Geconjugeerd bilirubine wordt getransporteerd naar gal → duodenum
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In darm wordt geconjugeerd bilirubine omgezet in urobilinogeen
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Deel urubilinogeen wordt omgezet in stercobiline → stoelgang
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Ander deel gaat via bloedbaan terug naar lever
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In nieren kan urobilinogeen omgezet worden tot urobiline → urine
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