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UNE MEDICAL BIOCHEMISTRY REVIEW EXAM QUESTIONS AND ANSWERS
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UNE MEDICAL BIOCHEMISTRY REVIEW EXAMQUESTIONS AND ANSWERS
Which enzymes are activated by high glucagon levels during fasting (insulin:
glucagon ratio <1)? - ANSWER: hormone-sensitive lipase
Ketonuria, hypoglycemia, and severe acidosis are the primary diagnostic
markers of type 1 diabetic ketoacidosis. Which of the following substances are
"ketone bodies" that would be raised in the serum or urine of a patient with this
condition? - Answer: D-3-hydroxybutyrate and acetoacetate.
What is the aim of cholesterol esterification inside the cell? (The conversion of
cholesterol into cholesteryl ester)
This change makes cholesterol more soluble in the plasma membrane.
b. This alteration does not alter the chemical characteristics of cholesterol.
C. Esterification is the first step in the production of cortisol.
Esterification traps cholesterol within the cell.
An individual goes to bed at 8 p.m. and doesn't get up until 9 a.m. the next day.
During this time, which of the following is the predominant oxidizable substrate
in skeletal muscle?
a) free fatty acids
B. Glycogen
C. Amino Acids
d. Lactate-free fatty acids
, A 22-year-old lady participating in a political protest goes on a hunger strike on
a conspicuous corner of a local park. During the first two weeks, she declines all
meal proposals with the exception of water. Which of the following fuel paths is
less likely to be used under given conditions?
a) β-oxidation
c. Ketogenesis.
C. Gluconeogenesis
d. lipolysis: ANSWER gluconeogenesis
In reverse cholesterol transport, HDL interacts with the ABCA1 transporter to
transfer cholesterol from the cell to the HDL. This also requires the action of
which of the following enzymes?
A. lipoprotein lipase
b. Cholesteryl Ester Transfer Protein (CETP)
c. Lecithin cholesterol acyltransferase (LCAT)
d. LDL receptor: lecithin cholesterol acyltransferase (LCAT)
A 16-year-old woman visits her health care physician for a follow-up
appointment. Her blood cholesterol was 255 mg/dL at her first visit three
months earlier, which is above normal. She is really disappointed because she
started a stringent eating plan in which she reduced all fats and cholesterol and
replaced them with a high carbohydrate diet. You inform her that high
carbohydrate diets can elevate blood triglyceride levels in some people. This
results in an increase in the synthesis of which of the following lipoproteins?
A. Chylomicrons
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