TESTBANK FOR CLAYTON’S BASIC
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PHARMACOLOGY FOR NURSES 19th EDITION
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BYMICHELLEWILLIHNGANZ CHAPTER 1-48
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Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz: Clayton’s Basic
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Pharmacology for Nurses, 19th Edition
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MULTIPLECHOICE h
1. Which name identifies a druglisted bythe US Food and
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DrugAdministration (FDA)?h h
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C h
The official name is the name under which a drug is listed by
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the FDA. The brand name, or trademark, is the name given to a
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drug by its manufacturer. The nonproprietary, or generic,
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name is provided by the United States Adopted Names
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Council.
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DIF: Cognitive Level: Knowledge
h REF: p. 9 h h h h
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care Environment h h h h h h h h h
TOP: Nursing Process Step: Assessment
h h CON: h h h
Patient Education h
2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names h h h h h h h
b. Natural Medicines Comprehensive Database h h h
c. United States Pharmacopoeia/National Formulary (USP NF) h h h h h
d. Drug Interaction Facts h h
ANS: C h
United States Pharmacopoeia/National Formulary contains information specific to nutritional
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supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based
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information on herbal medicines and herbal combination products; it does not include
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information specific to nutritional supplements. Drug Interaction Facts contains comprehensive
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information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge
h REF: p. 4 OBJ:3 h h h h h
h NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step:Assessment
h CON: Nutrition | Patient Education h h h h h h h
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons h h h
b. Drug Interaction Facts h h
c. Handbook on Injectable Drugs h h h
d. Martindale—The Complete Drug Reference h h h
ANS: A h
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
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therapeutic class. Monographs are formatted as tables to allow comparison of similar
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products, brand names, manufacturers, cost indices, and available dosage forms Online
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version is available.
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DIF: Cognitive Level: Knowledge
h REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 hNAT:NCLEX Client NeedsCategory: Physiological Integrity
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TOP: Nursing Process Step:Assessment
h CON: Safety | Patient Education | Clinical Judgment h h h h h h h h h h
4. Which drug reference contains monographs about virtually every single-entity drug available in
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the United States and describes therapeutic uses of drugs, including approved and unapproved
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uses?
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a. Martindale: The Complete Drug Reference h h h h
b. AHFS Drug Information h h
c. Drug Reference h
d. Drug Facts and Comparisons h h h
ANS: B h
AHFS Drug Information contains monographs about virtually every single-entity drug available
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in the United States and describes therapeutic uses of drugs, including approved and unapproved
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uses.
h
DIF: Cognitive Level: Knowledge
h REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 hNAT:NCLEX Client NeedsCategory: Physiological Integrity
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TOP: Nursing Process Step: Planning
h CON: Safety | Patient Education | Clinical Judgment h h h h h h h h h h
5. Which online drug reference makes available to healthcare providers and the public
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h a standard, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index h h
b. American Hospital Formulary h h
c. DailyMed
d. Drug Reference h
ANS: C h
DailyMed makes available to healthcare providers and the public a standard, comprehensive, up-
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to-date look up and downloadable resource about medicines. The American Drug Index is not
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appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
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The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge
h REF: p. 3 | p. 4 h h h h h h h OBJ:3 h
NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and CosmeticAct (1938) h h h h h h
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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b. Durham HumphreyAmendment (1952) h h h
c. Controlled SubstancesAct (1970) h h h
d. Kefauver Harris DrugAmendment (1962) h h h h
ANS: A h
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of
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all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
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drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
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safely without medical supervision and restricts their sale to prescription by a licensed
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practitioner. The Controlled Substances Act addresses only controlled substances and their
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categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
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safety. Drug manufacturers are required to prove to the FDAthe effectiveness of their products
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before marketing them.
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DIF: Cognitive Level: Knowledge
h REF: p. 5 Table l.3 h h h h h h
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under? a.
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I
b. II
c. III
d. IV
ANS: B h
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
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severe psychological and physical dependence. Schedule I drugs have high potential for abuse
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and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead
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to low to moderate physical dependence or high psychological dependence.
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Schedule IV drugs have low potential for abuse. Use may lead to limited physical or
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psychological dependence.
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DIF: Cognitive Level: Knowledge
h REF: p. 10 OBJ:2 h h h h h
h NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
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TOP: Nursing Process Step:Assessment
h CON: Patient Education |Addiction | Pain h h h h h h h h h
8. Which action would the FDAtake to expedite drug development and approval for an outbreak of
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smallpox?
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a. List smallpox as a health orphan disease. h h h h h h
b. Omit the preclinical research phase. h h h h
c. Extend the clinical research phase. h h h h
d. Fast track the investigational drug. h h h h
ANS: D h
Once the Investigational New Drug Application has been approved, the drug can receive highest
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priority within the agency, which is called fast tracking. A smallpox outbreak would become a
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priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
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research is not omitted. Extending any phase of the research would mean a longer time to develop
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a vaccine. The FDA must ensure that all phases of the preclinical and clinical research phase have
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been completed in a safe manner.
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DIF: Cognitive Level: Knowledge
h h h REF: p. 7 h h OBJ: 5 h
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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NAT: NCLEX Client Needs Category: Safe, EffectiveCare Environment
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TOP: Nursing Process Step: Assessment
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CON: Health Care Law | Health Care Policy | Infection | Care Coordination
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9. Which statement is true about over-the-counter (OTC) drugs?
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a. They are not listed in the USP NF.
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b. Aprescription from a healthcare provider is needed.
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c. They are sold without a prescription.
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d. They are known only by their brand names.
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ANS: C h
OTC medications do not require a prescription. A variety of names, both generic and trade, can be
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used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription drugs
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require an order by a health professional who is licensed to prescribe, such as a physician, nurse
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practitioner, physician assistant, or dentist.
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DIF: Cognitive Level: Comprehension
h REF: p. 2 OBJ:2 h h h h h
h NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
h CON: Patient Education h h h h h
10. Which is the most authoritative reference for medications that are injected?
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a. Martindale: The Complete h h
b. Handbook on Injectable Drugs h h h
c. DailyMed
d. Handbook of Nonprescription Drugs h h h
ANS: B h
The Handbook on Injectable Drugs is the most comprehensive reference available on the topic
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of compatibility of injectable drugs. It is a collection of monographs for more than 300 injectable
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drugs that are listed alphabetically by generic name.
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DIF: Cognitive Level: Knowledge
h REF: p. 4 OBJ:3 h h h h h
h NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step:Assessment
h CON: Clinical Judgment | Safety h h h h h h h
11. Which statement is true about Lomotil? h h h h h
a. Abuse potential for this drug is low. h h h h h h
b. Psychological dependency is likely. h h h
c. There is a high potential for abuse.h h h h h h
d. This drug is not a controlled substance.
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ANS: A h
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
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dependence liability compared with drugs in Schedule IV. Because abuse potential is low with a
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Schedule V drug, a prescription may not be required. Psychological dependency is not likely with
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a Schedule V drug. Schedule V drugs are classified as controlled substances.
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DIF: Cognitive Level: Knowledge
h REF: p. 5 Box 1.1 OBJ:2 h h h h h h h
h NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step:Assessment
h CON: Clinical Judgment | Safety | Patient Education
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12. Which medication ordered for a patient with a substance abuse history has the greatest risk
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for abuse? h h
a. Lomotil
