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Biol 232 Skeletal System Notes

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This is a comprehensive and detailed note on the skeletal system that contains necessary information for test prep!!

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  • October 12, 2024
  • 6
  • 2021/2022
  • Class notes
  • Prof. bradley
  • All classes
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anyiamgeorge19
Skeleton System Notes:

Human Skeleton:
 206 bones
 Axial and appendicular
 Cartilages:
o Hyaline cartilage: articular and costal cartilages
o Fibrocartilage: pressure absorbing discs
 Connective Tissue Proper:
o Major contributor to all synovial joint capsules
o Ligament: bone to bone
o Tendon: muscle to bone

Skeletal System Functions:
 Support
 Protection
 Movement (levers)
 Mineral storage (Ca2+)
 Blood cell formation (hemopoiesis)
 Model for bone growth
 Articulations

Classification of Bones:
 Flat bones:
o Ex: frontal bone
 Irregular bones:
o Ex: vertebrae
 Sesamoid bones:
o Ex: patella
 Short bones:
o Ex: tarsals and carpals
 Long bones:
o Ex: femur and humerus

Composition of Bones:
 Inorganic Constituents of Bone:
o Calcium hydroxyapatite mineral matrix
 Calcium carbonate and calcium phosphate
 About 60-70% dry bone weight
o Water
 Accounts for about 25-30% total bone weight
 Organic Constituents of Bone:
o Collagen fibers (specifically collagen type IV)

, o Epithelial, vascular and nervous tissues
o Bone cells (osteocytes, osteoblasts, osteoclasts)

Bone Remodeling:
 Bone is a very “dynamic” tissue
 In response to mechanical loads, stresses or strains, osteoclasts and osteoblasts
breakdown and rebuild bony tissue to accommodate
 Wolff’s Law

Forces on Bone:
 Compressive Strength:
o Ability to resist compressive forces
o Due to the mineral matrix of bony tissue
 Tensile Strength:
o Ability to resist tension forces
o Due to the collage component of bone

Functions of Skeletal Soft Tissues:
 Binding and support
 Protection
 Articulations (reduced friction)
 Flexibility

Bone Cells:
 Osteogenic cell:
o stem cell
 Osteoblast:
o Matrix-synthesizing cell responsible for bone growth
 Osteocyte:
o Mature bone cell that maintains the bone matrix
 Osteoclast:
o Bone-reabsorbing cell

Ossification:
 Creation of bone

Osteogenesis:
 Bone can be “created” one of two ways:
 Intramembranous Ossification:
o Formation of bone within a membrane
o Most skull and few other bones form this way
 Endochondral Ossification:
o Formation of bone within a cartilage precursor

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