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  • October 12, 2024
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Adams and Urban, Pharmacology: Connections to Nursing Practice, 2e Test
Bank
Chapter 60
Question 1
Type: MCSA

A common theme among all the antineoplastic agents is:

1. Their side effects.

2. Their ability to kill cancer cells.

3. Their drug interactions.

4. Their mechanism of action.

Correct Answer: 2

Rationale 1: A common theme of all antineoplastic agents is not their side effects, even though some might have
some similar side effects.

Rationale 2: A common theme of all antineoplastic agents is their toxicity—their ability to kill cancer cells.

Rationale 3: A common theme of all antineoplastic agents is not their drug interactions.

Rationale 4: A common theme of all antineoplastic agents is not their mechanism of action.

Global Rationale:

Cognitive Level: Remembering
Client Need: Physiological Integrity
Client Need Sub: Pharmacological and Parenteral Therapies
Nursing/Integrated Concepts: Nursing Process: Assessment
Learning Outcome: 60-1

Question 2
Type: MCSA

Classification of antineoplastics is difficult because:

1. The drugs kill cancer cells by different mechanisms and have characteristics from more than one class.

2. The drugs cannot always kill the cancer cells.

3. The drugs only have characteristics from one class, even though they kill by different mechanisms.

Adams and Urban, Pharmacology: Connections to Nursing Practice, 2e Test Bank
Copyright 2012 by Pearson Education, Inc.

,4. The drugs have various side effects.

Correct Answer: 1

Rationale 1: These are the reasons classification is so difficult.

Rationale 2: The drugs can kill cancer cells.

Rationale 3: They kill by different mechanisms and have characteristics from more than one class.

Rationale 4: This does not affect classification, and they often do have similar side effects.

Global Rationale:

Cognitive Level: Applying
Client Need: Physiological Integrity
Client Need Sub: Pharmacological and Parenteral Therapies
Nursing/Integrated Concepts: Nursing Process: Assessment
Learning Outcome: 60-1

Question 3
Type: MCMA

Many antineoplastic agents have characteristics of more than one class. Paclitaxel (Taxol) can be classified as
a(n):

Note: Credit will be given only if all correct choices and no incorrect choices are selected.

Standard Text: Select all that apply.

1. Natural product.

2. Taxane.

3. Mitotic inhibitor.

4. Cell cycle inhibitor.

5. Alkylating agent.

Correct Answer: 1,2,3,4

Rationale 1: Paclitaxel (Taxol) can be classified as a natural product (it was derived from a plant).

Rationale 2: Paclitaxel (Taxol) can be classified as a taxane (its chemical structure).

Rationale 3: Paclitaxel (Taxol) can be classified as a mitotic inhibitor (its mechanism of action).

Adams and Urban, Pharmacology: Connections to Nursing Practice, 2e Test Bank
Copyright 2012 by Pearson Education, Inc.

, Rationale 4: Paclitaxel (Taxol) can be classified as a cell cycle inhibitor.

Rationale 5: Paclitaxel (Taxol) is not classified as an alykylating agent.

Global Rationale:

Cognitive Level: Applying
Client Need: Physiological Integrity
Client Need Sub: Pharmacological and Parenteral Therapies
Nursing/Integrated Concepts: Nursing Process: Assessment
Learning Outcome: 60-1

Question 4
Type: MCSA

Which statement regarding the adverse effects of antineoplastic drugs is the most accurate?

1. They produce the most, but a small range, of adverse effects.

2. They produce the same amount of adverse effects as any other medication.

3. They produce the most serious adverse effects of any medication.

4. They produce the least amount of serious adverse effects of any medication.

Correct Answer: 3

Rationale 1: Antineoplastic drugs produce the most serious adverse effects of any class of medications, affecting
almost every system.

Rationale 2: Antineoplastic drugs produce the most serious adverse effects.

Rationale 3: Antineoplastic drugs produce the most serious adverse effects.

Rationale 4: Antineoplastic drugs produce the most serious adverse effects.

Global Rationale:

Cognitive Level: Applying
Client Need: Physiological Integrity
Client Need Sub: Pharmacological and Parenteral Therapies
Nursing/Integrated Concepts: Nursing Process: Assessment
Learning Outcome: 60-2

Question 5
Type: MCSA

Adams and Urban, Pharmacology: Connections to Nursing Practice, 2e Test Bank
Copyright 2012 by Pearson Education, Inc.

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