Frontier PC 707 Advanced Pharmacology Final Safety Exam Questions And Complete Answers
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Course
PC 707
Institution
PC 707
Frontier PC 707 Advanced Pharmacology
Final Safety Exam Questions And Complete
Answers
What are ADRs? What is the APRNs responsibility in ADRs? Adverse drug reactions 1)
pharmacological (predictable) 2) idiosyneratic (unpredicted/severe); APRN: document & record
specific reaction & drug; i...
benefits or reactions; goal of therapy -related drug class -MOA -features of specific drugs -how
do they get into body (PO, inject)-metabolized and excretion
, Frontier PC 707 Advanced Pharmacology
Final Safety Exam Questions And Complete
Answers
Know The World Health Organization (WHO) Six Step Model of Rational Prescribing 1-
clearance Increased blood flow to organs, increased GFR Increased renal excretion Decreased
gastric motility=longer transport times, increased bioavailability Ex) SSRI-3rd trimester
increased metabolism & increased excretion = increased amounts, more frequent dosing because
of increased excretion, and longer transport/distribution
Review physiologic changes in peds. Higher rate of metabolism; drugs are less protein
bound, higher water concentration= increased distribution. Dosing based on kg; Infants= organ
, Frontier PC 707 Advanced Pharmacology
Final Safety Exam Questions And Complete
Answers
immaturity which can increase toxicity (decreased metabolism & excretion); underdeveloped
blood brain barriar=drugs readily to CNS; PO drugs not absorbed well due to variable peristalsis
What is Beers list and STOPP Tools and use implications? BEERS-1991 used to identify
outweighs risk, use drug; Guidelines not protocols
Understand the impact of genomics and metabolism. Personalization of drug; each pt
responds differently to drugs based on individual genetic makeup; genetic data can guide
selection of drugs & avoid ADRs; cheek swab (inadequate efficacy & safety); especially
important for depression meds
What is a teratogen? Causing malformation of embryo-characterized by effect at gestation
time
Scheduled drugs and RX writing Scheduled: controlled substances (I-V); high potential
for abuse (some narcotic, some not) Prescription drugs: not all are scheduled, need a script;
cannot buy over the counter ex) PCN
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