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Polycystic Ovary Syndrome (PCOS) Exam Questions with 100%v Correct Answers
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Polycystic Ovary Syndrome (PCOS) ExamQuestions with 100%v Correct Answers
What issue with PCOS is often ignored by some health professions
psychical issues that can occur such as issues with body image, depression and anxiety
Low-Cho Diets & PCOS - Zhang et al (2019)
A meta analysis of 8 randomised trials with 327 patients
What was the inclusion criteria for Low-Cho diets & PCOS by Zhang et al (2019)
- PCOS based on Rotterdam Criteria
- Low-carbohydrate diet = less than 45% energy from carbohydrates
- control group = more than 45% energy from carbohydrates
What outcomes were they looking at in Zhang et al (2019) Low-Carbohydrates Diet & PCOS
study
- BMI
- Insulin resistance
- hormones FSH, LH, SHBG, testosterone
SHGB
sex hormone binding gonadotrophin
In Low-Cho diets & PCOS by Zhang et al (2019) how did they look at insulin resistance
using Homer insulin resistance
What were the findings from Low-Cho diets & PCOS by Zhang et al (2019)
being on a low carbohydrate diet led to a significant reduction in BMI, insulin resistance and
blood lipids which included total cholesterol and LDL_C
Low-Cho diets & PCOS by Zhang et al (2019) Stratified analysis also suggested what?
that low fat, low carbohydrate diets that lasted more than 4 weeks also increased FHS
and SHGB and decreased testosterone
Why do we want to see an increase in FSH in women with PCOS
, because often you see low levels in women with PCOS which is then perhaps what's
driving anovulation
Why do we want to see decreased testosterone in women with PCOS
because having a decrease suggests that there's lower circulating androgens
Thomson et al (2012) found that what percent of women with PCOS suffer from vitamin D
deficiency
65-87%
A large percentage of women with PCOS are Vitamin D deficient. What is one
explanation they think might explain this
because there are usually higher rates of overweight and obesity among PCOS, because vitamin
D is a fat soluble vitamin, that is sequestered in adipose tissue
Why is vitamin D thought to be so important
vitamin D receptors are found in the ovaries and endometrium which suggest that vitamin
D does play a role in female reproduction
Vitamin D is associated with what?
- dysregulation of testosterone, LH and FSH
- impaired ovulatory function
- dysregulated follicle development
- oxidative stress
A systematic review and meta-analysis was conducted looking at what happens if we
supplement PCOS patients with vitamin D. What did they compare?
vitamin D supplementation with metformin or placebo
Metformin
used to improve glucose metabolism and reduce insulin resistance in people with type
2 diabetes
Why are women often prescribed metformin
to help then with their weight loss and help improve insulin resistance or improving
insulin sensitivity
in the meta-analysis comparing Vitamin D with metformin or placebo, what was the vitamin
D supplement included
400-12,000 international units a day
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