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NUR 211 Anaemia Notes

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This is a comprehensive and detailed note on Anaemia for Nur 211.

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  • October 14, 2024
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  • 2020/2021
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  • Prof. j. garner
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Anemia
Anemia: occurs when oxygen delivery is inadequate due to:
 Deficient volume of healthy RBCs
 Blood loss, inadequate production, increased RBC destruction
 Decreased normal hemoglobin
 Nutritional deficiencies, physiological disorders


Anemia: result of pathological process most often the condition is linked to blood loss, impaired production of
RBC’s, or increased destruction of RBC’s *women are at greater risk


RBC carries O2 throughout the body (oxygen binds to hemoglobin)
Anemia occurs when oxygen delivery is inadequate due to a deficient volume of healthy RBC’s or a decrease
amount of normal hemoglobin


Pathophysiology and Etiology
 Anemia reduces oxygen-carrying capacity
 Etiology
 Iron deficiency is most common
 Risk factors
 Poor nutrition
 Menstruation
 Prevention
 Some are genetic and cannot be prevented
 Adequate nutrition prevents others
Anemia results in loss of oxygen reading cells and tissues which lead to tissue hypoxia. Tissue hypoxia triggers
increase in Heart Rate and Respirations rate. Increase HR promotes an increase in CO while increase in RR
allows for greater delivery of O2 to the lungs and blood. Tissue hypoxia cause angina, fatigue, dyspnea on
exertion, and night cramps.
***Severe anemia causes Heart Failure


Clinical Manifestation
Categorized by cause
 Blood loss
 Nutritional
 Hemolytic
 Bone marrow suppression
Each type has specific pathophysiology, manifestations
Types of Anemia

, 1. Blood loss Anemia
Loss of RBCs, other blood components
Acute blood loss: triggers compensatory mechanisms (increased HR, constriction of blood vessels) help to
maintain output
 Circulating RBCs of normal size, shape
Chronic blood loss: fluids shifts from the interstitial spaces into the vessels. This helps to prevent hypovolemia.
Blood viscosity is reduced which could cause a heart murmur.
 Depletes iron stores
 RBCs small, pale


Normocytic; normal size and shape RBC
Microcytic: small RBC
Hypochromic: pale RBC
Poikilocytosis: malformed RBC


Clinical manifestations
 Hypotension, tachycardia, decreased LOC, oliguria, systolic heart murmur


2. Nutritional Anemias
Iron is a key nutrient necessary for Hgb synthesis.
 Iron deficiency anemia
 Brittle, spoon-shaped nails; cheilosis; smooth, sore tongue, pica
3. Vitamin B12 deficiency anemia: impairs cell division and maturation of the cell nucleus
 Manifestations develop gradually
 Pallor, jaundice, weakness
 May progress to paresthesias, problems with proprioception
 Difficulty maintaining balance
4. Pernicious anemia: develops from a lack of gastric intrinsic factor (secreted by the gastric mucosa) IF binds
with b12 and travels with it to the ileum where the vitamin is absorbed.
 Diarrhea, smooth, sore beefy red tongue, numbness/tingling

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