Exam (elaborations)
Exam (elaborations) TOEFL
- Course
- Institution
provinding answerand treatment
[Show more]
Seller
Follow
catewairimu243
Content preview
3. ANEMIA OF CHRONIC DISEASE (INFLAMMATORY ANEMIA) - CORRECTANSWER-
Treatment of Anemia of Chronic Disease (ACD)
- Why treat?
- associated with __________ prognosis, particularly in patients with
__________________, _____________________________ and/or
______________________
- treatment options
management of ________________________________
______________________ agents
________ supplementation if concomitant IDA
________ transfusions - CORRECT ANSWER-Treatment of Anemia of Chronic
Disease (ACD)
- Why treat?
- associated with poor prognosis, particularly in patients with malignancy, chronic kidney
disease and/or heart failure
- treatment options
management of underlying conditions
erthropoietic agents
iron supplementation if concomitant IDA
RBC transfusions
Treatment of ACD: Erythropoietic Stimulating Agents (ESAs)
short term benefits
- correction of _____________
- avoidance of ____________________________ - CORRECT ANSWER-Treatment of
ACD: Erythropoietic Stimulating Agents (ESAs)
short term benefits
- correction of anemia
- avoidance of RBC transfusions
- goal for use of ESAs in CKD:
- patients with ND-CKD hgb >=10 :
- patients with ND-CKD hgb < 10 :
- patients with 5D-CKD (stage 5 CKD with dialysis) : - CORRECT ANSWER-- benefits
of avoiding transfusions and ESA side effects (stroke, vascular access loss)
- don't initiate ESA
- individualize the decision to initiate ESA based on Hgb
- if Hgb is 9-10, use ESA to avoid Hgb falling below 9
ESAs for Treatment of Anemia of CKD
- synthetic recombinant human _______________________
- goal: avoid/minimize need for ____________________________; this is a chronic
condition
, - ESA not shown to significantly or consistently improve ___________, quality of life or
overall patient well being
- available formulations
1)
2)
- monitoring: - CORRECT ANSWER-ESAs for Treatment of Anemia of CKD
- synthetic recombinant human erythropoietin
- goal: avoid/minimize need for RBC transfusions; this is a chronic condition
- ESA not shown to significantly or consistently improve fatigue, quality of life or overal
patient well being
- available formulations
1) epoetin alfa
2) darbopoetin alfa
- monitoring: monthly Hgb
ESA Initiation and Dosing
1) initiate ESA
- HD-CKD and PD-CKD:
- ND-CKD:
2) reduce/stop ESA
- HD-CKD and PD-CKD:
- ND-CKD:
3) Epoetin alfa dosing HD-CKD and PD-CKD: IV or SubQ
Epoetin alfa dosing ND-CKD: IV or SubQ
4) Darbepoetin alfa dosing
- HD-CKD and PD-CKD: IV or SubQ
- ND-CKD: IV or SubQ - CORRECT ANSWER-ESA Initiation and Dosing
1) initiate ESA
- HD-CKD and PD-CKD: Hgb < 10 g/dL
- ND-CKD: Consider if Hgb < 10 g/dL - only use if rate of Hgb decline would result in
transfusion
2) reduce/stop ESA
- HD-CKD and PD-CKD: Hgb approaches or exceeds 11 g/dL
- ND-CKD: Hgb exceeds 10 g/dL
3) Epoetin alfa dosing HD-CKD and PD-CKD: IV
Epoetin alfa dosing ND-CKD: IV or SubQ
4) Darbepoetin alfa dosing
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller catewairimu243. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
73216 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now