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OST 575 Parasites 1&2 Exam 2 Questions And Correct Answers
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OST 575 Parasites 1&2 Exam 2 Questions AndCorrect Answers
What is the key symptom of a giardiasis (giardia intestinalis) infection? - ANSWER Borborygmi
What is the infectious form of Giardia that is usually ingested in contaminated water? What is
the infectious dose of Giardia? - ANSWER Cysts
*infectious dose is SMALL < 10 cysts*
What is the replicating form of Giardia that "graze" on proximal small intestine, as
commensals, and reproduce by binary fission? - ANSWER Trophozoites
How can the cysts from Giardia be eradicated from contaminated water? - ANSWER boiling
disinfection
filtration
What is the clinical presentation of Giardia infection? - ANSWER onset 1-2 weeks after infection
*borborygmi*
Bloating, flatulence COMMON
Nausea
malaise
--> *usually self limiting*
Who is usually affected by Giardia? - ANSWER daycare center outbreaks
illness in international travelers
, backpackers and campers
immunocompromised
How is Giardia diagnosed? - ANSWER Stool exam (cysts, trophozoites)
Microscopy (1-3 exams)
Stool antigen detection (ELISA)
What is the treatment of Giardia? - ANSWER *tinidazole is first line* BUT
metronidazole is cheaper and more commonly used
What must be avoided after treatment of a Giardia infection? - ANSWER avoid lactose
containing foods for at least a month
What is the main symptom caused by an Amebiasis (entamoeba histolytica) infection? -
ANSWER Dysentery
How is Entamoeba histolytica transmitted? What is the infectious dose? - ANSWER cysts in
feces via food (food handlers, "night soil"), water, oral/anal sex
*ONLY TAKES ONE CYST TO CAUSE DISEASE*
Where do the Trophozoites of Entamoeba Histolytica reside in the human GI tract? - ANSWER
reside in colon and multiply there
What is the process called where the trophozoite from Entamoeba Histolytica is able to kill
both epithelial cells and inflammatory cells? - ANSWER Trogocytosis (vicious cycle of
decreased leptin levels = malnutrition)
What are the symptoms of a Entamoeba Histolytica infection? - ANSWER incubation period: 1-4
weeks
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