N115 Final Study Questions And Answers Complete Study Solutions 2024/2025 Updates
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Course
N115
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N115
N115 Final Study Questions And Answers Complete Study Solutions 2024/2025 Updates
Adverse effects of methylxanthines include all of the following except which one?
a. narrow therapeutic window and drug interactions
b. restlessness, insomnia
c. hepatic toxicity
d. nausea, vomiting, diarrhea A...
N115 Final Study Questions And Answers
Adverse effects of methylxanthines include all of the following except which one?
a. narrow therapeutic window and drug interactions
b. restlessness, insomnia
c. hepatic toxicity
d. nausea, vomiting, diarrhea ANS ANS: C
Which of the following describes the mechanism of action of omalizumab (Xolair), a new asthma
treatment that must be injected subQ?
a. inhibit antigen-induced release of immunoglobulin E (IgE) from lung tissue
b. inhibition of phosphodiesterase and bronchodilation
c. partial β-agonist activity results in smooth muscle relaxation
d. all of the above ANS ANS: A
According to the current guidelines for the diagnosis and management of asthma, which one of the
following medications is the first choice 'rescue' bronchodilator in asthma exacerbations?
a. ipratropium [Atrovent], an antimuscarinic
b. albuterol [Ventolin], a beta 2 agonist
c. epinephrine [Adrenaline], a non-selective sympathomimetic
d. salmeterol [Serevent], a long-acting beta 2 agonist ANS ANS: B
Which one of the following is FDA-approved only for COPD and not asthma?
a. albuterol [Ventolin], a beta 2 (b2 ) agonist
b. epinephrine [Adrenaline], a non-selective sympathomimetic
c. cromolyn [Intal], an anti-inflammatory agent
,d. ipratropium [Atrovent], an antimuscarinic ANS ANS: D
Which of the following is a common adverse effect of nasal decongestants?
a. tolerance with repeated use
b. restlessness, irritability, insomnia
c. rebound congestion
d. all of the above ANS ANS: D
Which adverse effect is prominent with first-generation antihistamines?
a. antimuscarinic effects
b. nausea
c. dry cough
d. all of the above ANS ANS: D
The leukotriene modifiermontelukast [Singulair] has which anti-inflammatory mechanism of action
for asthma treatment?
a. inhibit leukotriene synthesis by blocking 5-lipooxygenase
b. block leukotriene effects by antagonist action at leukotriene D4 receptors
c. decreased synthesis of inflammatory mediators
d. suppresses histamine release ANS ANS: B
Which of the following are true statements about long-acting beta2 agonists (LABA)?
a. May be taken in place of an inhaled corticosterioid
b. often given in combination with a short-acting beta2 agonists (SABA)
c. may be used to improve nighttime symptoms in asthma and COPD
,d. may be used to prevent exercise-induced asthma ANS ANS: C
Which of the following drug classes are used to treat both heart failure and hypertension?
Angioedema and dry cough may occur with which antihypertensives?
a. beta blockers
b. alpha 2 antagonists
c. calcium channel blockers
d. ACE inhibitors ANS ANS: D
Which of the following may be a good drug choice to treat hypertension in a man who also has
benign prostatic hypertrophy?
a. calcium channel blocker
b. thiazide diuretic
c. alpha adrenergic blocker
d. beta blocker ANS ANS: C
, Which of the following describe(s) the mechanism of action of angiotensin receptor blockers
(ARBs)?
a. bind to the angiotensin receptor in the endothelium
b. block production of the vasoconstrictor angiotensin II
c. increases bradykinin levels
d. b and c ANS ANS: A
Mr. Depp, a 66-year-old-African-American male, was recently diagnosed with primary hypertension
(BP 152/94 mmHg). He has no medical history of diabetes or chronic kidney disease. Which of the
following classes would be appropriate for the initial treatment of his hypertension based on the
guidelines from the "Eight Report of the Joint National Committee on Detection, Evaluation and
Treatment of High Blood Pressure" (JNC-8)?
a. Beta-blockers
b. ACE inhibitors
c. Calcium channel blockers
d. Angiotensin-II receptor blockers ANS ANS: C
Mrs. Simpsons, a 66-year-old White-Caucasian female, has primary hypertension (BP 172/95
mmHg). Her medical history includes type 2 diabetes and chronic kidney disease. She became
intolerant to lisinopril [Zestril]. The physician discontinued Mrs. Simpson's lisinopril therapy. Based
on the guidelines from the "Eight Report of the Joint National Committee on Detection, Evaluation
and Treatment of High Blood Pressure "(JNC-8), which of the following agents would now be an
appropriate selection for the treatment of Mrs. Simpson's hypertension?
a. prazocin [Minipres]
b. Propranol [Inderal]
c. Enalapril [Vasotec]
d. Losartan[Cozaar] ANS ANS: D
The antihypertensive drug clonidine has which of the following actions?
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