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MMSC 491 Exam 1- Questions and Answers 100% Correct
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MMSC 491 Exam 1- Questions and Answers 100% Correct
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MMSC 491 Exam 1- Questions and Answers 100%Correct
Wobble Postition Correct Ans-The third position in the triplet adn typically does not efect
whcih amino acid is formed
Silent Mutations Correct Ans-Change in 1 base of the nucleotide (typically in wobble) and
does not cause a change in the amino acid that is expressed
Nonsense Mutations Correct Ans-singluar base is changed and causes early termination in
the sequence adn now causes a "stop" codon to form
Missense Mutation Correct Ans-Changed in 1 base and causes a change in the amino acid
that is expressed
2 Types: Conservative and Nonconservative
Conservative Missense Mutation Correct Ans-Amino acid changes, but the amino acid that
is put in has similar properties/that behave similary to the original amino acid that was in
place from the biochemical stand point
Nonconservative Missense Mutation Correct Ans-The new amino acid that is placed has
different chemical properties from the original amino acid prior to mutations
Difference between Deoxyribose and Ribose Correct Ans-at the 2' psotion on the deozy
there is a hydrogen attached compared to Ribose that has an OH group
, MMSC 491 Exam 1- Questions and Answers 100%
Correct
Effects of Epigentic Alteration Correct Ans-1. Alters accessibility of DNA
2. Changes in gene Expression
Purines Correct Ans-Adenine and Guanine (has 2 rings)
Pyramidines Correct Ans-Cytosine, Thymine, and Uracil (Has 1 ring
DNA Bases Correct Ans-AGTC
RNA Bases Correct Ans-AGUC
Structure of ssDNA Correct Ans--Asymetric 5' and 3' end
-5'end = phospahate group
-3' end: Hydroxyl Group
DsDNA Correct Ans--Strands run antiparralel
-Runs 5'-3' with the oppsosite running 3'-5'
Hydrogen bonds between A &T Correct Ans-2 hydrogen Bonds
, MMSC 491 Exam 1- Questions and Answers 100%
Correct
Hydrogen bonds between G and C Correct Ans-3 hydrogen bonds
DNA Replication is Correct Ans-Semi-conservative
DNA Polymerase synthesizes in the Correct Ans-5'-3' direction
Leading strand of DNA Correct Ans-DNA is syntheiszed in a processive manner in the same
way as the replciation fork (5'-3')
Lagging Strand of DNA Correct Ans-DNA is syntheiszed in a back stitich way, by using
fragments because it is synthesized in backwards way, these fragments known as okazaki
Fragemnts
Classic DNA-Dependent Polymerase Correct Ans--Builds off the template
-Required for DNA Replication
-Alpha, delta, epsilon, Beta, and Gamma
Alpha DNA Polymerase Correct Ans-Initiates DNA syntheiss and participates in formation
of the okazawki fragments
Delta and Epsilon DNA Polymerase Correct Ans-Major DNA Polymerase that play major
role in DNA Replication and Repair
, MMSC 491 Exam 1- Questions and Answers 100%
Correct
Beta DNA Polymerase Correct Ans-Involved in DNA Repair
Gamma DNA Polymerase Correct Ans-Dedicatid to Mitochondrial DNA Repair and
Synthesis
RNA Dependent DNA Polymerases Correct Ans--Retrosposon Reverse Transcriptase
-Telomerase Reverse Transciptase
Involved in Retrosposon Reverse Transcription Correct Ans-Occasionly convert mRNA and
other RNA to cDNA that integrate into our genome that can give rise to new genes
Telomerase Reverse Transcriptase (TERT) Correct Ans--Replicates DNA at end of Linear
Chromsomes using RNA Template
-Ends of chromsomes are not replicated in DNA synthesis use seperate Process
Transcription Correct Ans--Synthesis of RNA
Messenger RNA (mRNA)
-Function end point of gene expression are RNA which include
a)tRNA
b)rRNA
c) ETC
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