Prite 2024 Part 2 Exam Questions &
Answers 10-0% Correct!!
a lesion to the left anterior lateral temporal lobe would result in the inability to __________ -
ANSWERidentify objects
What disorder was significantly more prevalent in mothers of patients with anorexia - ANSWEROCD
Which of the following neurotransmitters is stored in large dense-core vesicles
histamine
somatostatin
norepinephrine
epinephrine
gaba - ANSWERGABA, glutamate, glycine, ach, serotonin, dopamine, Norepi and epi and histamine
are all considered small molecule transmitters indicating that they are stored in small, clear,
membrane bound grandules called synaptic vesicles and mediate fast synaptic transmission
Somatostatin, hypothalamic releasing hormones, endorphins, enkephalins, and opioids comprise the
neuropeptide family of transmitters, sotred in large,dense core cesciles, modulate neuroal
communication by acting on cell surface receptors and are not recycled into the cell after secretions
small molecule transmitters and neuropeptides are often released from the same neuron and can act
on the same target
Drugs that fluoxtetine increases the drug levels of - ANSWERTCAs (increased risk of cardiac AE),
thioridazine (increased cardiac AE), benzos (increased sedation), carbamazepine, phenytoin
Which contemporary of Freud worked closely with him in developing the theory of hysteria -
ANSWERJosef Breuer
famous for his work w the young hysteric Anno O and coauthored a book w freud entiteld studies on
hysteria
Who coined the term schizophrenia
The principal mechanism of action of memantine is believed to be the blockade of current flow
through channels of N-methyl-d-aspartate (NMDA) receptors--a glutamate receptor subfamily
broadly involved in brain function
nicotinic receptors - ANSWEROn all ANS postganglionic neurons, in the adrenal medulla, and at
neuromuscular junctions of skeletal muscle
,Excitatory when ACh binding occurs
What deficits can you see with clock drawing - ANSWERDesign Copy:" Copy this design" • Frontal:
attention, planning. Motor coordination
• Right parietal: construct, gestalt. Damage leads to hemineglect
Difference between rationalization and intellectualization - ANSWERIntellectualization: use intellect
to avoid an emotional/affective experience (get cancer, spend all your time on internet learning
about it to avoid emotionally experiencing having cancer)
Rationalization: using rational explanations to justify an unacceptable behavior or belief ("I'm
allowed to take stacks of napkins home from McDonald's because they'll just throw them away
anyway")
What is isolation of affect? - ANSWERa defense mechanism in which you "think the feeling" instead
of feeling it.
ex. "i guess i'm angry at him" vs. expressed and experienced anger
Isolation: separate an idea from an affect ("isolation of affect" PRITE question has a patient who
blankly tells therapist that, as a child, his dad kicked a puppy to death. No affect in telling story
repression vs suppression (defense mechanisms) - ANSWER-repression is unconscious, not aware of
it happening. exclusion of unwanted experience or emotions
-suppression is conscious removal of awareness, this is like procrastinating or pushing things down
Repression: put an undesirable thought/feeling into the unconscious to avoid dealing with it. This is
different from suppression, which consciously avoids the thought. (Repression: unconsciously
forgetting a rape at the age of 5. Suppression: choosing not to think about the rape that happened at
age 5). Repression is similar to thought blocking, except no tension is observed with repression
• Suppression: consciously postponing discomfort (one child in car accident, rather than first rushing
to ER, suppresses fear and calls the other kids at home to make sure they are safe and cared for, then
goes to ER)
With loss of sleep, with happens with glucose tolerance - ANSWERdecreased glucose tolerance
other things that happen:
- increased cortisol levels
- decreased brain metabolic rate
- decreased host defense system
, - increased sympathetic activation
Which of the following is the best tool to localize genes of single or major effect within a family of
related individuals?
a. linkage analysis
b. association mapping
c. candidate gene studies
d. genome wide associated studies
e. comparative genomic hybridization - ANSWERLinkage analysis
Linkage Analysis: studies where in the genome (i.e., in which chromosomal region) a disease
mutation or susceptibility locus may reside. The likelihood that two loci on a chromosome will co-
segregate is inversely proportional to the distance between them (genes physically close to each
other shouldn't spereate during random crossover in meiosis). Measured using Logarithm of the
odds (LOD) with score of 3 (1,000:1 odds) as the threshold for declaring linkage
What are single nucleotide polymorphisms (SNPs)? - ANSWERSingle Nucleotide Polymorphisms
(SNPs): Disorders may arise not from one single problematic gene, but the cumulative effect of many
small one-letter variations, or SNPs. Identified with genome-wide studies. Low predictive value thus
far.
genome-wide association studies - ANSWERtrack SNP patterns among individuals who share a
particular trait or disorder
What was his main contribution - ANSWEREugen Bleuler
the 4 As : looseness of associations, affective flattening, autism, and ambivalence
What was Kurt Schneider's contribution to psychiatry - ANSWERknown for his "first rank" symptoms
of schizophrenia, including thought insertion and withdrawal, thought broadcasting, 2 voices having
a dialogue, delusions of passivity
What is kava kava? - ANSWERUsed to treat depression and anxiety, also used as a sleep aid.
Dont use with alcohol, used with alprazolam may cause coma.
Levadop can increase parkinson like symptoms.
Made from the root of the kava (piper methysticum) plant
used for its sedative and anesthetic qualities and commonly ingested as beverage. Several
commercial brands available. Like benzos and alcohol, acts on GABA receptors. Long term use linked
to liver toxicity, SHOULD NOT BE TAKEN WITH ETOH, BENZOS, BARBS DUE TO CNS DEPRESSION
