Exam (elaborations)
Pharmacology exam 4 Ch 32, 45, 46, 50 Nur138 ECPI Questions and Answers
Pharmacology exam 4 Ch 32, 45, 46, 50 Nur138 ECPI
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Pharmacology exam 4 Ch 32, 45, 46, 50Nur138 ECPI
gastric iior iiduodenal iiulcers iithat iiinvolve iidigestions iiof iithe iiGI iimucosa iiby iithe iienzyme
iipepsin ii- iiAnswers ii-peptic iiulcer iidisease iiPUD
What iiare iithe iitypes iiof iiacid-controlling iidrugs? ii- iiAnswers ii-antacids
H2 iiantagonists
proton iipump iiinhibitors
bacterium iifound iiin iithe iiGI iitract iiof ii90% iiof iipatients iiw/duodenal iiulcers iiand ii70% iiof
iipatients iiw/gastric iiulcers: ii- iiAnswers ii-helicobacter iipylori ii(H.pylori)
What iiis iithe iifirst iiline iitherapy iifor iiH.pylori? ii- iiAnswers ii-treated iiwith iia iiproton iipump
iiinhibitor iiPPI iiand iiantibiotics
GI iilesions;
decreased iibloodflow;
mucosal iiischemia;
hyperfusion;
reperfusion iiinjury
can iibe iicaused iiby iiNG iitube iiand/or iiventilators ii- iiAnswers ii-Stress-related iimucosal
iidamage
Many iiantacid iimedications iialso iicontain iithe iiantiflatuent iidrug ii___. ii- iiAnswers ii-
simethicone
Many iialuminum iiand iicalcium iibased iiantacid iiformulations iialso iiinclude ii___ iiwhich
iicontributes iito iithe iiacid iineutralizing iicapacity iiand iialso iicounteracts iithe ii_____
iieffects iiof iialuminum iiand iicalcium. ii- iiAnswers ii-magnesium; iiconstipating
basic iicompounds iiused iito iineutralize iistomach iiacid;
contain iisalts iiof iialuminum, iimagnesium, iicalcium iiand/or iisodium ii- iiAnswers ii-antacids
calcium iiantacids iimay iilead iito iithe iidevelopment iiof ii_______ iiand iiincreased iigastric
iiacid iisecretions. ii- iiAnswers ii-kidney iistones
Patients iiwith iirenal iifailure iimust iiavoid iiantacids iicontaining iiwhat? ii- iiAnswers ii-
magnesium
calcium
,What iiis iia iihighly iisoluble iiantacid iiform iiwith iia iiquick iionset, iibut iia iishort iiduration iiof
iiaction? ii- iiAnswers ii-sodium iibicarbonate
What iiare iithe iiMOA iifor iiantacids? ii- iiAnswers ii-neutralize iiacid iisecretions;
promote iigastric iimucosal iidefense iimechanism;
stimulate iisecretions iiof: ii
mucus: iiprotective iibarrier iiagainst iiHCI
bicarbonate: iibuffer iiacidic iiproperties iiof iiHCI
prostaglandins: iiprevent iiactivation iiof iiproton iipump
What iido iiantacids iiNOT iido? ii- iiAnswers ii-prevent iithe iioverproduction iiof iiacid
What iiare iicontraindications iifor iiantacid iiuse? ii- iiAnswers ii-known iiallergy;
renal iifailure;
electrolyte iidisturbances;
GI iiobstruction
have iia iiconstipating iieffect;
often iirecommended iifor iipatients iiw/renal iifailure ii(easily iiexcreted) ii- iiAnswers ii-
aluminum iisalts
commonly iicauses iidiarrhea;
contraindicated iiw/renal iifailure;
Milk iiof iiMagnesia ii- iiAnswers ii-magnesium iisalts
H.pylori iiis iibelieved iito iibe iithe iiunderlying iicause iibehind iimost iiulcers. ii(T iior iiF) ii-
iiAnswers ii-True
There iiis iinot iiany iireason iiyou iicannot iigive iia iipatient iiwith iiheart iifailure iisodium
iibicarbonate iiantacids? ii(T iior iiF) ii- iiAnswers ii-False
What iifood/drink iishould iibe iiavoided iiif iia iipatient iiis iihaving iitrouble iiwith iistomach
iiacid/heartburn? ii- iiAnswers ii-caffeine
chocolate
alcohol
large iifatty iimeals
What iiantacids iiare iirecommended iiif iia iipatient iihas iirenal iicompromise iibecause iiit iiis
iieasily iiexcreted? ii- iiAnswers ii-aluminum iicontaining
sodium iicontaining
What iimight iia iipatient iiexperience iiif iitheir iipH ii<7.35? ii- iiAnswers ii-excess iihydrochloric
iiacid ii(HCI) iisecreted iiby iiparietal iicells;
heart iiburn
pH iihas iia iinormal iirange iiof? ii- iiAnswers ii-7.35-7.45
, What iitype iiof iidrug iiinteraction iitakes iiplace iiof iithe iistomach iiacid iipH iiis iiincreased? ii-
iiAnswers ii-increased iiabsorption iiof iibasic iidrugs;
decreased iiabsorption iiof iiacidic iidrugs
What iitype iiof iidrug iiinteraction iitakes iiplace iiif iithe iistomach iiacid iipH iiis iidecreased? ii-
iiAnswers ii-decreased iiabsorption iiof iibasic iidrugs;
increased iiabsorption iiof iiacidic iidrugs
What iitype iiof iidrug iiinteraction iioccurs iiif iithe iiurinary iipH iiis iiincreased? ii- iiAnswers ii-
increased iiexcretion iiof iiacidic iidrugs;
decreased iiexcretion iiof iibasic iidrugs
What iiis iithe iiMOA iifor iihistamine2 iireceptor iiantagonists ii(H2 iireceptor iiblockers? ii-
iiAnswers ii-block iithe iiH2 iireceptor iiof iiparietal iicells;
reduce iihydrogen iiion iisecretion iifrom iiparietal iicells;
increase iistomach iipH
What iihas iibeen iishown iito iidecrease iithe iieffectiveness iiof iiH2 iireceptor iiantagonists? ii-
iiAnswers ii-smoking
What iiis iiZollinger-Ellison iisyndrome? ii- iiAnswers ii-rare iicondition iicharacterized iiby
iigastrin-producing iitumors iiin iithe iiduodenum iiand/or iipancreas iithat iilead iito iiover-
secretion iiof iigastrin, iiwhich iilead iito iigastric iiand iiduodenal iiulcers
What iiis iia iicommon iitreatment iifor iiZollinger-Ellison iiSyndrome, iiGERD, iiPUD, iierosive
iiesophagitis, iias iian iiadjunct iifor iiGI iibleeding ii? ii- iiAnswers ii-H2 iireceptor iiantagonists:
Cimetidine ii(Tagamet)
Nizatidine ii(Axid)
Famotidine ii(Pepcid)
Ranitidine ii(Zantac)
Cimetidine ii(Tagamet) iican iicause iiissues iiwith iidrugs iithat iihave iia iinarrow iitherapeutic
iirange iisuch iias: ii- iiAnswers ii-theophylline;
warfarin;
lidocaine;
phenytoin
What iiis iithe iiMOA iifor iiproton iipump iiinhibitors ii(PPI)? ii- iiAnswers ii-prevent iimovement
iiof iihydrogen iiions iifrom iiparietal iicells iiinto iistomach;
temporarily iiblocking iiall iiacid iisecretion
***should iibe iitaken iion iian iiempty iistomach***
What iiis iiused iias iia iishort iiterm iitreatment iiof iiactive iiduodenal iiand iibenign iigastric
iiulcers; iiZollinger-Ellison iisyndrome, iiNSAID iiinduced iiulcers; iiprophylactic iifor iistress
iiulcers? ii- iiAnswers ii-proton iipump iiinhibitor iiPPI
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