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NUR 601 (Immune System) EXAM QUESTIONS AND ANSWERS
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NUR 601 (Immune System) EXAM QUESTIONS AND ANSWERS
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NUR 601 (Immune System) EXAM QUESTIONS AND ANSWERS1. Three functions of immune system? Prevent
pathogens from
entering
Eliminate
pathogens from
body
Provide memo-
ry against future
infections from
same pathogen
2. What is an antigen? Substances that
cause the body to
elicit immune re-
sponse & produce
antibodies to fight
them off.
3. What is an antibody? Proteins usually
found in the blood
that detect anti-
gens, bind to them
and destroy them
4. When are live-attenuated vaccines (e.g., MMR) con- 1.
traindicated? Immunosuppres-
sion (e.g.,
immunocompro-
mised pts, HIV)
2. Chemotherapy
3. Pregnancy
5. What are the two classifications of antibodies? Pro- Immune globulins
duced by? or gamma globu-
lins; produced by
plasma cells (lym-
phocytes) in re-
sponse to anti-
gens
,NUR 601 (Immune System) EXAM QUESTIONS AND ANSWERS
6. What are the three major functions of antibodies? (1) Neutralization
(binding)
(2) Antibody op-
sonization (mark-
ing)
(3) Complement
system
7. What is neutralization? Blocking the as-
sociation of the
pathogen with
their targets, ren-
dering the toxin in-
effective
8. What is opsonization? Marking a
pathogen (e.g.,
bacteria) for in-
gestion & destruc-
tion by a phago-
cyte, an immune
cell
9. What is the complement system? a major protein
system that en-
hances the inflam-
matory response
10. What are the four ways the complement system (a)Increasing vas-
works? cular permeability,
(b)Promoting
chemotaxis
(movement of
WBCs to the area
of inflammation),
(c)Encouraging
phagocytosis of
foreign bodies,
(d)Helping break-
, down of the for-
eign cell (cytoly-
sis)
11. What are the five types of immunoglobulins? IgG, IgA, IgM, IgE,
IgD
12. Which immunoglobulin is most common in blood? IgG; all bodily flu-
Where is it found, and in what percent? ids; 70%; most
common in blood
13. What is the first antibody to increase during initial or IgM
primary immune response to an antigen?
14. Where is IgA found in the body? Mostly in blood,
but also sali-
va, the secretions
and mucous mem-
branes of the res-
piratory and diges-
tive tracts and in
colostrum
15. What are three functions of IgE? Allergic response
Defense against
parasites
Causes release of
histamines
16. What cells does IgD attach to and activate? B cells
17. What is the first line of defense of innate immunity? External defense:
(2) skin and secre-
tions
18. What is the second line of defense of innate immuni- Internal defense:
ty? (6) 1. Phagocytes:
macrophages and
WBC's
2. Inflammatory
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