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CCTC review Study Guide with Complete Solutions

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CCTC review Study Guide with Complete Solutions Procedure for liver transplant - Answer-Anastomosis of the inferior vena cava, portal vein, hepatic artery, and the biliary connection via a duct to duct anastomosis ( choledochocholeclochostomy) Etiology of renal dysfunction immediately post op(...

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  • October 16, 2024
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CCTC review Study Guide with
Complete Solutions

Procedure for liver transplant - Answer✔✔-Anastomosis of the inferior vena cava, portal vein,

hepatic artery, and the biliary connection via a duct to duct anastomosis (

choledochocholeclochostomy)


Etiology of renal dysfunction immediately post op(liver tx) - Answer✔✔-Hypotensive episodes,

blood loss, high renal vein pressure intraoperatively and postoperatively due to

hemodynamically instability or sepsis.


Leading cause of non graft related death for liver recipients - Answer✔✔-Cardiorespiratory

failure


Which immunosuppressants cause HTN - Answer✔✔-Calcineurin inhibitors or corticosteroids


Which lab to monitor with fever post tx - Answer✔✔-Crp- c reactive protein because protein

present with acute inflammation and sepsis


Indicative of rejection - Answer✔✔-Light stools and dark urine,


Indicative of poor graft function s/p liver transplant - Answer✔✔-High lactate and acidosis, high

ALT/AST, PT >25 sec and continues to rise after vit k and FFP




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,EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024


type 2 diabetes - Answer✔✔-More common, occurs in adulthood, characterized by insulin

resistance. As resistance rise, beta cells are eventually unable to produce necessary amount of

insulin to lower and maintain normal blood glucose levels.


type 1 diabetes mellitus - Answer✔✔-diabetes in which no beta-cell production of insulin occurs

and the patient is dependent on insulin for survival


Goal of pancreas transplant - Answer✔✔-To restore normoglycemia, halt or prevent secondary

complications of diabetes


Indications for pancreas transplant alone (PTA) or pancreas after kidney (PAK) transplant -

Answer✔✔-Type 1 DM manifested by poor metabolic control, especially hypoglycemic

unawareness for many years. On insulin and C-peptide at or < 2 ng/ml or on insulin and C-

peptide at or greater than 2ng/mg and BMI at or less than maximum allowable BMI (currently

28) and pancreatic exocrine insufficiency.


Indications for Simultaneous pancreas-kidney (SPK) transplant - Answer✔✔-Diagnosis of

diabetes or pancreatic exocrine insufficiency with renal insufficiency


Immunosuppressive medications are covered by which part of Medicare? - Answer✔✔-

Medicare part B


Standard immunosuppressive for pancreas transplant recipients typically includes: -

Answer✔✔-Tacrolimus(prograf, FK506), mycophenolate mofetil (cellcept), prednisone(steroid)




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Reason why native pancreas left in place during pancreas tx - Answer✔✔-Allows the exocrine

function of native pancreas to be preserved.


Enteric Drainage( ED) post pancreas transplant - Answer✔✔-More common, difficult to detect

rejection, donor portal vein anastomosed to recipients SMV(superior mesenteric vein), donor

duodenal segment attached to recipients jejunum, pancreases produces 2L of fluid drainage,

pancreatic enzymes excreted thru the stool


Advantages of Enteric drain (ED) post pancreas transplant - Answer✔✔-More physiologic, fewer

metabolic imbalances because pancreatic secretions are reabsorbed, less post-op complications


Bladder Drainage (BD) post pancreas transplant - Answer✔✔-Easier to monitor for rejection

with urine amylase, may cause dehydration and cystitis. Direct monitoring of graft exocrine

function, easier to perform biopsy, less invasive if complications arise.


Disadvantages of Bladder Drainage (BD) post pancreas transplant - Answer✔✔-Dehydration,

cystitis, UTIs, metabolic acidosis, urine leak, hematuria, 35% go on to need enteric conversion,

pancreatitis


Patients with anastomotic leak post pancreas transplant may present with what? - Answer✔✔-

Elevated serum amylase levels


C-peptide normal range - Answer✔✔-0.8-3.1


What is a sign of late rejection post pancreas transplant? - Answer✔✔-Hyperglycemia




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