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APEA Endo questions and answers rated A+ 2024/2025
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APEA Endo questions and answers rated A+ 2024/2025
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APEA EndoWhen patients administer everyday insulin (Humulin R U-500), they have to be trained: -
ANS10 gadgets of Humulin R U-500 is equal to 10 devices on a U-500 insulin syringe.
Radioiodine therapy is secure to administer to: - ANSA 30-12 months-vintage man who
desires natural fatherhood-used to tx hyperthyroidism and does now not reason infantility or
delivery defects in the offspring of tx'd pts
A pt who has Addison's sickness has received a prescription for fludrocortisone.
Fludrocortisone acts via: - ANSRegulating salt and water balance-mineralocorticoid indicated
as partial substitute therapy for pts with primary or 2ndary adrenocortical insufficiency
Methimazole for the tx of Graves' disorder is contraindicated in pts: - ANSWho are
pregnant-can cause fetal harm while administered, can comfortably go the placental
membranes
Which of the subsequent medicinal drugs may also reason gynecomastia? - ANSEnalapril
(Vasotec)-ACE inhibitors may reason gynecomastia
A pt is commenced on a sulfonylurea (i.E. Glyburide). The NP informs the pt that
sulfonylureas are in all likelihood to: - ANSReduce microvascular activities-additionally low in
cost
Disadvantages-produce hypoglycemia and motive weight gain
Thiazolidinedione (TZD) medicinal drugs: - ANSIncrease insulin sensitivity-by acting on
adipose, muscle & liver to increase glucose utilization and reduce glucose production
Pts taking dipeptidyl-peptidase-four (DDP-IV) inhibitors for the tx of T2DM do NOT
mechanically need to be monitored for: - ANSWeight loss-Januvia, Onglyza, Tradjenta now
not likely to purpose weight reduction or weight benefit
The predicted hemoglobin A1V reduction for pts who're commenced on
dipeptidyl-peptidase-four (DDP-IV) inhibitors which include sitagliptin (Januvia) is: -
ANS0.6%
DDP-IV inhibitors including alogliptin (Nesina): - ANSSuppress glucagon secretion and
increase insulin secretion
Sulfonylurea-stimulate the release of insulin from functioning beta cells
Biguanides-decrease hepatic glucose manufacturing, lower intestinal absorption of glucose,
and enhance insulin sensitivity
, Prior to the admin of methimazole (Tapazole) the NP need to reap a baseline: - ANSCBC-tx
for hyperthyroidism, CBC & liver profile ought to be obtained
A pt is started out on exenatide (Byetta) for T2DM. Byetta have to be d/c'd if the pt reveals: -
ANSPersistent abd pain, radiating to the again-monitored for sx of acute pancreatitis
Sulfonylureas including glyburide (Micronase) are notably metabolized: - ANSIn the
liver-mainly via CYP 450
A forty eight-12 months-vintage pt is started on metformin (Glucophage) for T2DM. The most
anticipated hemoglobin A1C reduction after initiation of this remedy is: - ANS2%- ordinary
anticipated decrease in A1C is 1-2%
Insulins recommended for use in insulin pump transport systems consist of: - ANSApidra &
Humalog-simplest rapid performing insulins are secure for continuous IV use
The generic call for Victoza is: - ANSLiraglutide-GLP-1 agonists
A pt who's commenced on a glucagon-like peptide (GLP-1), which includes Victoza, need to
be informed that this magnificence of medicines may additionally: - ANSIncrease satiety-put
off gastric emptying & promote weight loss
Pts who're receiving radioiodine therapy for hyperthyroidism must be cautioned to: -
ANSAvoid touch with young youngsters for numerous days-radiation emits from the body
keep away from youngsters & pregnant ladies
Pts taking thiazolidinedione (TZD) medications should be monitored for: - ANSFluid retention
& weight benefit-may additionally precipitate or exacerbate HF in some pts through causing
dose-associated fluid retention
Levothyroxine use inside the 1st trimester of pregnancy: - ANSMay require an growth in
dose-due to changes of endogenous maternal thyroid hormones
Exenatide (Byetta) is classed as: - ANSGLP-1
Gynecomastia is NOT probable to be caused by: - ANSClonazepam
Ketoconazole, finasteride, spiro, lavender/tea tree oil might also purpose this
Pt receiving insulin detemir (Levemir) are at higher threat for developing: -
ANSHypokalemia-reasons a shift in K+ from the extracellular area to the intracellular area
The mechanism of action by means of which metformin (Glucophage) improves glucose
tolerance is: - ANSDecreased intestinal absorption of glucose-additionally improves insulin
sensitivity by way of increasing peripheral glucose uptake and usage
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