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Exam (elaborations)

MRCPsych Paper A: Questions With Solutions (100% Correct)

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  • MRCPsych
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  • MRCPsych

MRCPsych Paper A: Questions With Solutions (100% Correct)

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  • October 17, 2024
  • 14
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MRCPsych
  • MRCPsych
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Zendaya
MRCPsych Paper A: Questions With Solutions (100%
Correct)

Dorsolateral Prefrontal syndrome Right Ans - Executive dysfunction,
Diminshed planning

Parotitis - seen in which mental disorder Right Ans - 20-year old with Hx of
Bulimia Nervosa that stopped purging 2 days ago presenting with painless
swelling on her face - Dx

Medial prefrontal Syndrome Right Ans - Poverty of speech , Paucity of
spontaneous behaviour

Orbitofrontal syndrome Right Ans - Poor impulse control, Explosive
outbursts

Ideomotor apraxia Right Ans - the inability to carry out a simple motor
activity in response to a verbal command, even though this same activity is
readily performed spontaneously

Ideational apraxia Right Ans - an impairment in the ability to carry out a
sequence of actions, even though each element or step can be done correctly

Visuopatial agnosia Right Ans - Loss of sense of "whereness"

Alpha-synuclein (SNCA) gene Right Ans - Located on chromosome 4

Parkin (PRKN) gene Right Ans - Located on chromosome 6

Genetic causes of Parkinson Disease Right Ans - LRRK2
PARK7
PINK1
PRKN
SNCA
(gene mutations)

Mutated genes in FTD Right Ans - C9ORF72, proteins tau (MAPT),
Progranulin (GRN)

, C9ORF72 gene location Right Ans - 9q21.2 - associated to FTD and ALS

MAPT gene location Right Ans - 17q21.31 - associated to FTD, Parkinson-
17 and PSP

GRN location Right Ans - 17q21.31 - associated to FTD

Huntington gene (HTT) location Right Ans - Chromosome 4

Mamillary Body alpha ketoglutarate Right Ans - Structure implied in
Korsakoff syndrome

Raphe Nuclei Right Ans - Storage site of serotonin

Kleine-Levin Syndrome Right Ans - Sleeping beauty syndrome -
Hypothalamic pathology

Normal development milestones Right Ans - Crawling: 6-9 months
Verbal production: 12 months
Ability to build a tower of 6 cubes: 2 years
Ability to use simple sentences: 3 years
Copying a square: 4 years

Memantine MOA Right Ans - N-Methyl-D-Aspartate (NMDA) Receptor
Antagonist and 5HT3 receptor antagonist

Galantamine MOA Right Ans - selective and reversible Acetylcholinesterase
inhibitor and nicotine modulator

Rivastigmine MOA Right Ans - pseudo-irreversible acetylcholinesterase
inhibitor

Donepezil MOA Right Ans - selective reversible AChE inhibitor

Trazodone → Mirtazapine Right Ans - Cross taper with caution

Fluoxetine → Tranylcypromine (MAOI) Right Ans - Withdraw and wait for
5-6 weeks

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