Final Exam Review for NURS 6521
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What category antidepressants is the following meds: Citalopram, Escitalopram, FLuoxetine,
Fluvoxamine, Paroxetine, Sertraline, Vortioxetine? - ✔Selective Serotonin Reuptake
Inhibitors
What category antidepressants is the following meds: Desvenlafaxine, Duloxetine,
Levomilnacipran, Venlafaxine. - ✔Serotonin-norepinephrine Reuptake Inhibitors
What category antidepressants is the following meds: Amitriptyline, clomipramine,
desipramine, doxepin, imipramine, maprotiline, nortriptlyine, protiptyline, trimipramine. -
✔Tricyclic Antidepressants
These meds block muscarinic cholingeric receptors and can therby cause an array of
anticholinergic effects such as dry mouth, blurred vision, photophobia, constipation,
urinary hesitancy and tachycardia. - ✔Trycyclic
The combination of TCA and _______ can lead to severe hypertension, owing to excessive
adrengergic stimulation of the heart and blood vessels. - ✔MAOI
What are the three mood-stablizer drugs for bipolar? - ✔Lithium, carbamazepine,
valproic acid
What three types of drugs are used in treatment for bipolar? - ✔Mood
stabalizers, antispychotics, and antidepressants
,What is the drugs of choice for acute manic episodes? - ✔Lithium and valprate in
combination with a SGA
What is the choice regimen for acute depressive episodes? - ✔a mood stabilizer, SGA, and
an antidepressant
This mood stabilizer has a low therapeutic threshold and a short half life making toxicity a
high risk therefore needs to be divided into daily doses - ✔Lithium
What are normal lithium levels - ✔below 1.5
How often should lithium levels be drawn? - ✔3-6 months
When should you draw lithium levels? - ✔in the morning, 12 hours after evening dose
can reduce the incorporation of iodine into thyroid hormone nad can inhibit thyroid
hormone secretion. - ✔Lithium`
Chronic lithium use has been linked to ? - ✔Renal toxicity
This side effect occurs in 50 to 70% of patients taking lithium - ✔Polyuria
These drugs promote sodium loss and therby increase the risk of toxicity. - ✔Diuretics
These drugs can increase lithium levels as much as 60% - ✔NSAIDS
, THis drug was the first antiseizure agent approved for bipolar and sometimes replaces lithium
as drug of choice but can cause serious or fatal hepatotoxicity and pancreatitis. -
✔Divalproex Sodium (Valproate)
What other antieleptic drug is approved for treatment and prevention of manic episodes
in BPD? - ✔Carbamazepine
These Sedative drugs potentiate the actions of y-aminobutyric acid (GABA) an
inhibitory neurotransmitter found throughout the CNS. - ✔Benzos
Because benzos can act by amplifying the actions of GABA rather than directly mimicing GABA it
is safer than what drug that directly mimics GABA? - ✔Barbituates
What three things are benzos used for ? - ✔Anxiety, insomnia, and seizures
benzos can cause __________ which is impaired recall of events that take place after dosing. -
✔Anterograde Amnesia
Benzo like drug that is our most widely used hypnotic and is approved for insomnia.
- ✔Zolidem (Ambien)
This drug is the first representative of a new class of hynotics, the pyrazolopyrimidines made for
insomnia. - ✔Zaleplon (Sonata)
Which drug is liike zaleplon and zolpidem, binds selectively with the benzo-1 receptor on
the GABA receptor-chloride channel complex and thereby enhances the depressant action
of endogenous GABA. - ✔Eszopiclone (Lunesta)
This drug is a relatively new hypnotic with a unique mechanism of action: activation
of receptors for melatonin. - ✔Ramelteon (Rozerem)
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