Exam Bank Questions and Answers for Psychopharm Chapter 15 Already Passed
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Psychopharm Chapter 15
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Psychopharm Chapter 15
Exam Bank Questions and Answers for Psychopharm Chapter 15 Already Passed
What are the classes of antidepressants available in the U.S.? - Answers 1) TCA's (Tricyclic antidepressants)
2) Monoamine oxidase inhibitors (MAOI's)
3) SSRI's (Selective serotonin reuptake inhibitors)
4) SNRI's (Seroto...
Tricyclic antidepressants (TCAs) are not used commonly in the U.S. for depression. What are the current
usual indications for low dose TCAs? - Answers Chronic pain and sleep disorders
Which class of antidepressants has the highest sexual side effects for both men and women? - Answers
SSRI's (30-60% of patients experience sexual side effects)
Which two antidepressants have minimal sexual dysfunction? - Answers Wellbutrin and Remeron
Which SSRI has an active metabolite and can stay in the body for at least a month after being
discontinued? - Answers Prozac (Fluoxetine)
Name the SNRIs - Answers Effexor, Pristiq, Cymbalta, and Remeron
How are the SNRIs different from the SSRIs? - Answers They effect both norepinephrine and serotonin
What class of antidepressants is most dangerous in overdose cases? - Answers TCAs
Which class of antidepressants is most likely to worsen conditions of BPH (enlarged prostate) and
chronic constipation? - Answers TCA's
Other than anticholinergic side effects (dry mouth, constipation, urinary retention), TCA is sedating and
can cause _________________ secondary to postural hypotension (AKA orthostasis). - Answers
Dizziness and memory impairment
Which of the SSRIs has the most anticholinergic effects and may worsen the BPH or constipation? -
Answers Paxil
Atomoxetine (Strattera) is a norepinephrine reuptake inhibitor. It is not FDA approved for depression. It
has an FDA indication for what? - Answers ADHD
, Why is bupropion (Wellbutrin) contraindicated in patients with eating disorders? - Answers Higher
incidence of seizures
Which class of antidepressants has the risk of hypertensive crisis when high tyramine foods or drinks are
consumed, as well as with the concurrent use of over the counter decongestants? - Answers MAOI
(Monoamine Oxidase Inhibitors)
_________________ is a monoamine oxidase inhibitor (MAOI) transdermal patch FDA approved for the
treatment of depression. - Answers Ensam
What are the main neurotransmitters involved with depression? - Answers Norepinephrine, serotonin,
and dopamine
Why does it take weeks for antidepressants' onset of action? - Answers Down-regulation of receptors
Stimulants such as dextroamphetamine (Dexedrine) are sometimes prescribed for depression. Their
common side effects are: - Answers Insomnia, increased blood pressure and heartrate
Explain why the efficacy of antidepressants for severe depression may be overestimated in drug studies
using the Hamilton Depression Scale (HAM-D)? - Answers Any drug that successfully lowers depression
by half is considered effective, but the patient may still be depressed
How long should antidepressants be continued upon resolution of the 1st depression episode? -
Answers 6 months after the symptoms are resolved
What is the chance of relapse with depression about 2-3 episodes? - Answers 90%
Sertraline should be taken with food because - Answers Better absorption and less nausea
Why is it important not to start mono therapy with antidepressants for patients with Bipolar
depression? - Answers Because the use of only an anti-depressant can cause a manic episode in a bi-
polar patient.
What is considered an adequate trial of an antidepressant before switching to another agent? - Answers
6 weeks at an adequate dose
What classes of antidepressants are best for the treatment of anxiety? - Answers SSRIs or SNRIs
Which antidepressant is not used for panic disorder? Why? - Answers Bupropion (Wellbutrin), because it
does not target serotonin.
Which antidepressants can cause insomnia and should not be taken near bedtime? - Answers Viibryd,
Prozac, Wellbutrin, Effexor
Other than the TCAs, which class of antidepressants are used for chronic neuropathic pain? - Answers
SNRIs (much better than SSRIs)
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