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NAPLEX Review questions with correct answers.
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NAPLEX Review questions with correctanswers
What is the equation for corrected phenytoin? - correct answer -CP= measured serum
phenytoin/(0.2*albumin)+0.1
What is the principle intracellular cation? - correct answer -potassium
Principle extracellular is Sodium
How many mL in a teaspoon? - correct answer -5 mL
how many mL in a tablespoon - correct answer -15 mL
how many mL in a cup? - correct answer -240 mL
how many mL in an ounce? - correct answer -29.6 mL
how many mL in a pint? - correct answer -473 mL
how many mL in a gallon? - correct answer -3785 mL
How do we calculate mols or mmols of a substance? - correct answer -mol= g/MW
mmol= mg/MW
How many mg are in one grain? - correct answer -65 mg/grain
How many lbs in a kg? - correct answer -2.2lbs/kg
,What is the conversion of aminophylline to theophylline? - correct answer -we multiply the
aminophylline by 0.8 to get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - correct answer -divide the amount of
theophylline by 0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - correct answer -ratio strength= 100/%
strength
How do we get the percent strength from the ratio strength? - correct answer -% strength= 100/ratio
strength
How do we convert PPM to percent strength? - correct answer --PPM to % strength, move decimal left 4
places
-% strength to PPM, move decimal place right 4 places
specific gravity - correct answer -SG= grams of substance/mL
mEq - correct answer -mEq= mg x valence/MW
Which chemicals have 2 valences? - correct answer -Calcium carbonate
Calcium chloride
Ferrous sulfate
Magnesium sulfate
mOsmol/L - correct answer -mOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number of particles x
1000
Equation for anion gap` - correct answer -Na - (Cl + Bicarbonate)
,How much elemental calcium is found in calcium carbonate and calcium citrate? - correct answer -40%
in carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate? - correct
answer -fumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - correct answer -ANC= WBC x [(%segs + %bands)/100]
What is the formula to determine a patient's total energy expenditure? - correct answer -TEE= BEE x
activity factor X stress factor
What is the equation to find pH of a weak acid? - correct answer -pH = pKa + log(salt/acid)
What is the equation to find pH of a weak base? - correct answer -pH = (pKw - pKb) + log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - correct answer -pH > pKa more
acid is ionized
pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
How are the ABG measurements written out on the exam? - correct answer -pH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - correct answer -pH = 7.35-7.45
HCO3 = 38-42
pCO2 = 22-28
, When adding calcium and phosphate to TPN what should be considered? - correct answer --Use calcium
gluconate over calcium chloride because it is less reactive and a lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - correct answer -weight in kg/height in meter^2
BSA - correct answer -BSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is needed for TPN?
- correct answer -10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
How many kcals do amino acids and dextrose provide in TPN? - correct answer -Amino acids 4 kcal/gram
dextrose 3.4 kcal/gram
what is the pKa? - correct answer -The pKa is the pH at which half the drug is 50% ionized. This is half the
neutralization or equivalence point. The neutralization or equivalence point is at a much higher pH and
occurs when the acid has been neutralized.
what is the correct calcium equation? - correct answer -Corrected Ca = [(4.0-albumin) x 0.8] + serum
calcium
What is the equation for absolute bioavailability? - correct answer -F= 100 x (AUC extravascular/AUC
intravascular) x (Dose intravascular/Dose extravascular)
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