, 10/18/24, 8:37 AM MN553 Unit 7 Quiz/MN 553 Pharm Unit 7 Quiz Questions and Answers Latest Updated 2024-2025 update / get it 100% accur…
Sacubitril
Valsartan (Entresto)
ACEs
What medications will ARBs
you see in stage D heart
failure (5) Inotropes: dobutamine
Ventricular assisting devices
Transplantation
Hospice
Inhibit angiotensin-converting enzyme (ACE) which
Pharmacodynamics of
results in decreased production of both angiotensin
ACEs
II and aldosterone
Can lower vascular resistance without decreasing
cardiac output (CO) or glomerular filtration rate
What are the special
(GFR)
characteristics of ACEs
Does not produce reflex tachycardia
Strong evidence for CV and cerebrovascular risk
Uses for ACEs
reduction, heart failure, and slowing renal disease
Improves oxygenation to heart muscle, decreases
Outcomes of ACEs on inappropriate remodeling of heart muscle after MI
the heart or with HF, reduces effects of diabetes on the
kidneys
Outcomes of ACEs on Improves insulin sensitivity, does not affect glucose
insulin metabolism or raise serum lipid levels
Prevents formation of AT II and decreases
Outcomes of ACEs in pulmonary vascular resistance by decreasing
patients with angina retention of sodium and water and reducing
extracellular fluid and preload
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