NR565/ NR 565 FINAL EXAM ADVANCED PHARMACOLOGY 2024 EXAM COMPLETE 220 QUESTIONS WITH DETAILED VERIFIED ANSWERS (100% CORRECT) /ALREADY GRADED A+ CHAMBERLAIN

Midterm Exam: NR565/ NR 565 Advanced Phar 8 8 8 8 8 8


macology Care of the Fundamentals Exam | 8 8 8 8 8 8


Questions and Verified Answers (2023/ 2024 Update)- 8 8 8 8 8 8


Chamberlain 8




When is it used - ASCVD Risk Score - ANSWER-
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In children a screening should be done between ages 9 and 11 and then ag
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ain at ages 19 and 21. For adults every 5 years after the age of 20. Some pe
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ople are at greater risk like those with diabetes and a risk score greater than
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87.5% and should be screened more often
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ezetimibe- when can it be used? - ANSWER- 8 8 8 8 8 8 8



pregnancy/breastfeeding can be use in monotherapy or as adjunct therapy 8 8 8 8 8 8 8 8 8 8



with a statin or a fibrate
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What is ezetimibe? - ANSWER-Cholesterol Absorption Inhibitor-
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lowers cholesterol levels by decreasing the amount of cholesterol that is a
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bsorbed from the small intestine, so that there is less intestinal cholesterol
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delivered to the liver. Does not affect triglycerides
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lifestyle changes for high cholesterol - ANSWER-
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Lifestyle changes are non drug measures used to lower LDL. Four main is
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sues are diet, exercise, weight control, and smoking cessation
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If a patient wanted to minimize side effects, which drug classification is a
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good choice? - ANSWER-Non-statins-
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8fibrates, Ezetimibe, Bile acid sequestrants. Statins are generally well toler
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ated and side effects are uncommon. Some patients develop headache, flat
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ulence, constipation, or GI disturbances, but these effects are usually mild
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and transient
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, Midterm Exam: NR565/ NR 565 Advanced Phar 8 8 8 8 8 8


macology Care of the Fundamentals Exam | 8 8 8 8 8 8


Questions and Verified Answers (2023/ 2024 Update)- 8 8 8 8 8 8


Chamberlain 8




Therapeutic action of organic nitrates (nitroglycerin) - ANSWER-
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direct relaxant effect on vascular smooth muscles, and the dilation of coro
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nary vessels improves oxygen supply to the myocardium. The dilation of
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peripheral veins, and in higher doses peripheral arteries, reduces preload a
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nd afterload, and thereby lowers myocardial oxygen consumption.
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promote vasodilation 8




Contraindications for ranolazine - ANSWER- 8 8 8 8


Agents that inhibit CYP3A4 can increase the levels of ranolazine and ther
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eby increase the risk of torsades de pointes. These things include: grapefr
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uit juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal
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drugs, and some CCB. Most CCB but not amlodipine can increase levels
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of ranolazine. Drugs that prolong the QT interval can increase the risk of t
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orsades de pointes. (quinidine, sotalol).
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At what age can statins be prescribed? - ANSWER-
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avoid statin use in children under the age of 10
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CCB role with variant angina - ANSWER-
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promote relaxation of coronary artery spasm, increasing cardiac oxygen s
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upply


what medication can be added for patients with worsening symptoms of H
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F? - ANSWER-aldosterone antagonist-
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promotes myocardial remodeling and fibrosis, help with symptoms
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, Midterm Exam: NR565/ NR 565 Advanced Phar 8 8 8 8 8 8


macology Care of the Fundamentals Exam | 8 8 8 8 8 8


Questions and Verified Answers (2023/ 2024 Update)- 8 8 8 8 8 8


Chamberlain 8




CCB stable angina - ANSWER-
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promote relaxation of peripheral arterioles, decreasing afterload and reduc
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ing cardiac oxygen demand
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A 41 year old patient comes into the clinic complaining of increased heart
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rate after starting nitro patches for stable angina. What would an appropria
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te response be?
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1. lets lower the dose and frequency of use
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2. I will prescribe a BB to help with this
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3. Next time this happens, lie down and practice deep breathing, this will b
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ring your heart rate down - ANSWER-2-
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I will prescribe a BB to help with this
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What do CYP450 inhibitors and reducers do when not used correctly/wha
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t would patient experience? - ANSWER-
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increased side effects, adverse reactions and toxicity
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A 55 year old male comes into the clinic with a gouty arthritis. He states th
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at he has one flareup a year. Your response is:
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1. I will prescribe you glucocorticoids to help with inflammation
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2. Lets start you on prophylactic therapy colchicine.
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3. It will be helpful to take an NSAID to start with to help relive some in
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flammation. I'll prescribe naproxen. - ANSWER-3- in patients with
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, Midterm Exam: NR565/ NR 565 Advanced Phar 8 8 8 8 8 8


macology Care of the Fundamentals Exam | 8 8 8 8 8 8


Questions and Verified Answers (2023/ 2024 Update)- 8 8 8 8 8 8


Chamberlain 8




infrequent flareups, being less than three per year, treatment of symptoms
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is all thats needed. NSAIDS are the first line agent for relieving pain of an
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acute gout attack. 8 8




A patient comes in stating that he tried NSAIDS to relieve a gouty attack b
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ut it hasnt helped. He asks, "what are my options?" He further states that h
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e has attacks every few years but when he does NSAIDS do not help. Your
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response is:
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1. I can prescribe a glucocorticoid (prednisone) and that will bring down t
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he inflammation and pain.
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2. Have your tried increasing your dosage of NSAIDS and drink plenty o
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f water?
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3. Lets start by making some changes in your diet, can you tell me what y
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ou eat regularly? - ANSWER-1
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3- can also be correct but BEST answer
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Colchicine is considered for long term treatment if a person has how many
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gouty attacks per year? - ANSWER-three or more
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Colchicine should not be taken with what medications? - ANSWER-
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statins, CYP3A4 inhibitors
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adverse effects of colchicine - ANSWER- 8 8 8 8 8


nausea, vomiting, diarrhea, myelosuppression, myopathy, rhabdomyolysi
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s