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NR565/ NR 565 Advanced Pharmacology Care of the Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8 Questions and Verified Answers Chamberlain ||Complete A+ Guide$15.49
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NR565/ NR 565 Advanced Pharmacology Care of the Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8 Questions and Verified Answers Chamberlain ||Complete A+ Guide
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NR565/ NR 565
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NR565/ NR 565
NR565/ NR 565 Advanced Pharmacology Care of the Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8 Questions and Verified Answers Chamberlain ||Complete A+ Guide
NR565/ NR 565 Advanced Pharmacology Care of the
Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8
Questions and Verified Answers Chamberlain
1. Signs and symptoms of hypothyroidism:Face is pale, puffy, and expression- less.
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Skin is cold and dry.
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hair is brittle, and hair loss occurs.
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Heart rate and temperature are lowered. The patient lethargy, fatigue, and intoler-
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ance to cold.
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Mentation may be impaired. v v v
2. Signs and symptoms of hyperthyroidism:Heart Rate is Rapid; Possible ar-
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rhythmia/angina v
Nervousness, insomnia, rapid thought flow, and rapid speech
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Skeletal muscles may weaken and atrophy
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Metabolic rate is raised, resulting in increased heat production, increased body
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temperature, intolerance to heat, and skin that is warm and moist
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Weight loss occurs if caloric intake fails to match the increase in metabolic rate
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, v/
21
1
3. Severe hypothyroidism:Myxedema
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4. Hypothyroid Treatment:Levothyroxine is the drug of choice for
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v most patients who require thyroid hormone replacement.
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5. Levothyroxine (Synthroid) Therapeutic Goal:Resolution of signs and symp-
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v toms of hypothyroidism and restoration of normal laboratory values for serum
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v thyroid-stimulating hormone (TSH) and free thyroxine (T4).
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6. Major forms of hyperthyroidism:Graves disease and toxic nodular goiter
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v (also known as Plummer disease).
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7. Graves Disease:Most common cause of excessive thyroid hormone secretion
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8. What adjunctive therapy is good to prescribe to control symptoms of
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v hyper- thyroidism other than thyroid specific medications?:²-Blockers and
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v nonradioac- tive iodine may be used as adjunctive therapy.
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²-Blockers suppress tachycardia by blocking ²-receptors on the heart.
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v Nonradioactive iodine inhibits synthesis and release of thyroid hormones.
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,9. Monitoring needs and intervals for Levothyroxine:Check TSH 6-8 weeks after
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initiating therapy and after any dosage change.
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Check TSH at least once a year after serum TSH is stabilized.
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10. Hyperthyroid Treatment:thionamide drugs—methimazole and propylthiouracil
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v (PTU)—suppress synthesis of thyroid hormones. v v v v
11. Methimazole Therapeutic Goal:(1) reduction of thyroid hormone
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v production in Graves' disease, (2) control of hyperthyroidism until the effects of
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v radiation on the thyroid become manifest, (3) suppression of thyroid hormone
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v production before subtotal thyroidectomy, (4) treatment of thyrotoxic crisis.
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, 12. Monitoring needs and intervals v v v v for Methimazole:Check CBC with
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v differential if signs or symptoms of infection. Check LFTs if signs or symptoms of
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v liver dysfunc- tion.
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13. High Risk Patients for Methimazole:Should be avoided in the first trimester
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v of pregnancy.
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14. Methimazole Toxicity:Agranulocytosis is the most dangerous toxicity. v v v v v v
15. PTU High Risk Warning:Carries a risk for liver toxicity. Although rare, the
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v FDA recommends against using as a first-line treatment due to potential for
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v hepatic toxicity. v
16. Effects of maternal hypothyroidism on offspring and appropriate patient
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v teaching related to need for treatment.:Can cause delay in mental
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v development and derangement of growth. In the absence of thyroid hormones,
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v the child develops a large and protruding tongue, potbelly, and dwarfish stature.
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v Development of the nervous system, bones, teeth, and muscles is impaired.
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17. Congenital Hypothyroidism Treatment:requires replacement therapy with
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v thyroid hormones. If treatment is initiated within a few days of birth, physical
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v and mental development will be normal.
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