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CSCC Pharmacology: Exam 1 (Review For Final) Questions And Answers With Verified Solutions Rated A+ $10.99   Add to cart
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CSCC Pharmacology: Exam 1 (Review For Final) Questions And Answers With Verified Solutions Rated A+
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CSCC Pharmacology: Exam 1 (Review For Final) Questions And Answers With Verified Solutions Rated A+

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  • October 19, 2024
  • 8
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • CSCC
  • CSCC

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CSCC Pharmacology: Exam 1 (Review
For Final) Questions And Answers With
Verified Solutions Rated A+
plasma half life (T1/2) - ANSWER✔✔descriptive of duration
-time for concentration of a med to decrease by one half


increased T1/2 =? - ANSWER✔✔increased excretion time = increased duration of
effects


onset - ANSWER✔✔time it takes to produce therapeutic effects


therapeutic range - ANSWER✔✔between minimum effective serum concentration
and toxic serum concentration


factors effecting excretion - ANSWER✔✔-decreased renal or hepatic function
-blood flow
-ionization
-lipid solubility
-drug protein complexes
-metabolic activity
-pH
-resp, glandular, or biliary activity


first pass effect - ANSWER✔✔oral drugs reach hepatic portal system prior to
reaching target tissue and may be inactivated

, prodrug - ANSWER✔✔drug that is activated by being metabolized (i.e. losartin,
benazepril)


hepatic microsomal enzyme system (p450-system) - ANSWER✔✔inactivates
drugs and accelerates excretion
**anything that effects this system effects drug metabolism**


primary site of drug metabolism - ANSWER✔✔liver


what drugs don't cross the blood-brain barrier easily? - ANSWER✔✔antitumor
drugs


what drugs DO cross the blood-brain barrier? - ANSWER✔✔-sedatives
-anticonvulsants
-antanxiety


displacement - ANSWER✔✔drug shifts another from a binding site and alters
effect
1A + 2 = 1 + 2A


antagonism - ANSWER✔✔causes a blocked or opposite effect
1+1=0 OR 1+1=-2


synergism - ANSWER✔✔action is more than total effect
1+1=4

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