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Quality Control FACTS NMTCB Practice Questions and Answers 2024
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Quality Control FACTS NMTCB Practice
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Quality Control FACTS NMTCB PracticeThe percentage of radioactivity in a preparation originating from the desired radionuclide
is called __________ purity – answer radionuclides
The radionuclides purity of 99mTc __________ during the day because of the longer
physical half-life of 99Mo compared with 99mTc. - answer decreases
An important cause of impurity in 123I preparations is __________. - answerI-124
A multichannel analyzer may be used to assess radionuclides purity by evaluating the
__________ of the sample - answer energy spectrum
The energies of 99Mo photons are __________ and __________. - answer740 keV;
780 keV
A simple, common method used to evaluate for the presence of 99Mo in 99mTc
samples uses a dose calibrator and __________. - answera lead shield (pig) to
differentially absorb the low-energy photons, while allowing the energetic 99Mo photons
to pass
The percentage of total radioactivity present in a preparation in the desired chemical
form is called the __________ purity. - answerradiochemical
If it is suspected that gastric activity on a bleeding scan is a result of free pertechnetate,
then one should image the __________ to confirm - answerthyroid
The most common means of evaluating radiochemical purity is by use of __________. -
answerinstant thin layer chromatography
A common source of chemical impurity that originates from the 99Mo/99mTcO4 −1
generator is __________. - answeraluminum from the alumina column
The presence of excess amounts of aluminum in a 99mTc-sulfur colloid preparation
leads to excess uptake in this organ of the body. - answerThe lungs (SC)
The presence of excess amounts of aluminum in a 99mTc (MDP) preparation leads to
excess uptake in this organ of the body - answerThe liver (MDP)
The presence of aluminum in a generator eluate can be tested by__________. -
answerindicator paper (aurintricarboxylic acid)
, The permissible quantities of aluminum in a fission 99Mo generator eluate are
__________. - answerless than 10 µ/mL eluate
The presence of excess amounts of stannous ion in a 99mTc-MDP preparation leads to
excess uptake in this organ of the body. - answerliver ( excess uptake)
Macroaggregated albumin should be of what particle size? - answer90% between 10
and 90 µm diameter. (but none should be larger than 150um)
. Fever-producing toxins that often originate in gram-negative bacteria and may
contaminate radiopharmaceuticals are called __________. - answerpyrogens
The rapid method of testing for pyrogens is __________. - answerthe limulus
amebocyte lysate (LAL) assay
(which uses the blood of the horseshoe crab, Limulus polyphemus)
The formal method of testing for pyrogens is by __________. - answerinjecting the
sample into rabbits and monitoring their temperature
The absence of viable microbes within a radiopharmaceutical is called __________. -
answersterility
Is endotoxin *much more* or *much less* toxic when radiopharmaceuticals are
administered into the cerebrospinal fluid (CSF) compared to systematically administered
preparations? - answermuch more
When there are increased counts at the *periphery* of the scintillation crystal due to
internal reflection of light at the edges, the phenomenon is called __________. -
answeredge packing
Uniformity flood images of each gamma camera should be performed on a __________
basis - answerdaily (gamma camera uniformity)
When the aluminum cover around a scintillation crystal is breached, the flood images
can appear spotty because of __________ of the crystal - answerhygroscopic
degeneration
The effect of a nonfunctioning photomultiplier tube (PMT) on a flood field is
__________. - answerthe presence of a discrete cold region
The term for tuning an energy window to the spectrum of a given isotope is
__________. - answerpeaking
The width of the measured spectrum for a particular gamma (γ) peak is a measure of
the __________ of the gamma camera. - answerenergy resolution
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