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UTT NURS 3303 Exam 2 Questions 100% Solved.

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©SIRJOEL EXAM SOLUTIONS 10/11/2024 1:41 PM X-Linked Dominant Disorder - answerEX: Fragile X syndrome Multifactoral Disorders - answer- multiple factors required for disease expression - cases occur sporadically in pedigree - not easily predicted - run in families, siblings - influenced by e...

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  • October 20, 2024
  • 44
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NURS 3303
  • NURS 3303
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©SIRJOEL EXAM SOLUTIONS
10/11/2024 1:41 PM



UTT NURS 3303 Exam 2 Questions 100%
Solved.


Genetics - answer✔the study of genes and their role in inheritance determines how certain traits

or conditions are passed from one generation to another


genomics - answer✔study of all of an individuals genes (the genome) and how they interact with

each other and the persons environment


Heterozygous (regarding inheritance patterns) - answer✔2 DIFFERENT alleles for a single trait




NO disease or A carrier


Homozygous (regarding inheritance patterns) - answer✔2 IDENTICAL alleles for a single trait

in the same location




AFFECTED


Punnet Squares - answer✔% of probability of having a disorder

, ©SIRJOEL EXAM SOLUTIONS
10/11/2024 1:41 PM


*are needed to figure out SGD because the probability isn't the same for all offsprings


Single Gene Disorders - answer✔classified by inheritance patterns (autosomal

recessive/dominant, X-linked)




single-gene controls a specific function (color blindness)




may have systemic effects (cystic fibrosis, Tay-Sachs, PKU)


Autosomal Recessive Disorder - answer✔*both parents must pass on defective gene*




to produce a homozygous affected child;

- parents may be heterozygous & unaffected and are termed CARRIERS

-parents may be homozygous & affected




Homozygous Recessive child has the disorder

Heterozygous child (1 normal & 1 abnormal allele) no clinical signs of disease, is a carrier




EX: cystic fibrosis, sickle cell disease, Tay-Sachs, PKU

, ©SIRJOEL EXAM SOLUTIONS
10/11/2024 1:41 PM


Autosomal Dominant Disorders - answer✔*Inheritance of ONE ALLELE causes disorder


*Only one parent needs to carry allele




-No carriers; unaffected parents do not transmit the disorder

-Some conditions become evident later in life; allele for disorder may have been passed on to

next generation before Dx of disease in parent ~ termed delayed lethal genotype




EX: Huntington's Cholera, polycystic kidney dz, familial hypercholesterolemia, Marfans

(symptoms vary)


X-Linked Recessive Disorders - answer✔- allele carried on X chromosome


- Manifested in heterozygous males

- heterozygous females are carriers

- homozygous females may be affected

- inheritance may appear to skip generations




EX: Duchenne Muscular Dystrophy, color blindness, classic hemophilia A (men mostly carry

this, rare in women)

, ©SIRJOEL EXAM SOLUTIONS
10/11/2024 1:41 PM


X-Linked Dominant Disorder - answer✔EX: Fragile X syndrome


Multifactoral Disorders - answer✔- multiple factors required for disease expression


- cases occur sporadically in pedigree

- not easily predicted

- run in families, siblings

- influenced by environmental factors




EX: cleft palate, diabetes, hydrocephalus, anacephaly, cancer, CAD, congenital hip dislocations


Chromosomal Disorders - answer✔Downs Syndrome (47 chromosomes) - Most common cause

of birth defects in US


Developmental Disorders - answer✔- occur during pregnancy


- most vulnerable during 1st trimester

- Causes: toxins, drug/alcohol exposure, some viral infections, hypoxia


Congenital anomalies - answer✔- present at birth, show up months/yrs later


- genetic, inherited or developmental disorders

- usually result from error during meiosis ~ DNA fragments are lost or misplaced

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