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ANTIBIOTICS NURSING PHARMACOLOGY. THE LATEST EXAM REVISION QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+) (2024 UPDATE) 100%
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ANTIBIOTICS NURSING PHARMACOLOGY. THE LATEST EXAM REVISION QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+) (2024 UPDATE) 100%

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  • October 20, 2024
  • 37
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • Nursing pharmacology
  • Nursing pharmacology

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ANTIBIOTICS NURSING PHARMACOLOGY. THE LATEST

EXAM REVISION QUESTIONS AND CORRECT ANSWERS

(ALREADY GRADED A+) (2024 UPDATE) 100%

Tobramycin - ANSWER- short-term IM or IV treatment, ophthalmic, and as a nebulizer

solution.


Aminoglycosides Adverse effects CNS - ANSWER- ototoxicity, possible irreversible deafness,

vestibular paralysis from drug effects on the auditory nerve.

Confusion, depression, disorientation

Numbness, tingling and weakness


Aminoglycosides Adverse effects Renal - ANSWER- may progress to renal failure


Direct glomerulus toxicity, drug molecules cause damage to kidney


Aminoglycosides Adverse effects - ANSWER- bone marrow depression


Aminoglycosides Adverse Effects GI - ANSWER- n/v, diarrhea, weight loss, stomatitis, and

hepatic toxicity. Direct GI irritation, loss of normal flora (superinfection, toxic effects in the

mucous membrane and liver as drug is metabolized).


Aminoglycosides Adverse Effects Cardiac - ANSWER- palpitation, hypotension, and

hypertension.

,Aminoglycosides Adverse effects hypersensitivity - ANSWER- purpura, rash, urticaria, and

exfoliative dermatitis.


Aminoglycosides drug-drug interactions - ANSWER- most have synergistic bactericidal effect

(given w/ penicillins, cephalosporins or ticarcillin avoid combining aminoglycosides with potent

diuretics.


Aminoglycosides drug to drug - ANSWER- when given with anesthetics, nondepolarizing

neuromuscular blockers, succylcholine, or citrate anticoagulated blood, increased neuromuscular

blockage with paralysis is possible.


Aminoglycosides drug to drug - ANSWER- patient is for surgery, indicate prominently on the

patient chart the fact that aminoglycosides has been given provide extended monitoring and

support after surgery.


Carbapenems - ANSWER- new class of broad-spectrum antibiotics (bactericidal) g (+) & g (-

) inhibit cell membrane synthesis in susceptible bacteria serious infection caused by susceptible

bacteria.


Carbapenem - ANSWER- -penem indicated for treating serious intraabdominal, urinary tract,

skin, and skin structure, bone and joint, and gynecological infection.


Carbapenems - ANSWER- beta lactamase against s pneumoniae when penicillin is resistant


-not for MRSA.


Carbapenems - ANSWER- rapid IM absorption


IV peak levels achieved after infusion average half-life: 1-4 hrs

,Carbapenems Pharmacokinetics - ANSWER- distributed throughout the body


Excreted unchanged in the urine. Not known if it crosses the placenta and breast milk.


Aminiglycosides - ANSWER- bactericidal, for gram-negative and aerobic bacilli. Inhibit

protein synthesis.


Aminoglycosides (TAI) - ANSWER- irreversibly bind to a unit of bacteria ribosomes


Leads to misreading of genetic code and cell death.


Aminoglycosides - ANSWER- treat serious infection caused by susceptible strains of gram-

negative bacteria.


Aminoglycosides meds - ANSWER- streptomycin neomycin kanamycin gentamicin

tobramycin.


Aminoglycosides TAI - ANSWER- treat serious infections that are susceptible to penicillin

when penicillin is contraindicated.

Can be used in severe infections before culture and sensitivity tests have been completed


Aminoglycosides Pharmacokinetics - ANSWER- -poor GI absorption


-rapid IM absorption

-Peak within 1 hour

-Ave half-life of 2-3 hrs.


Aminoglycosides Pharmacokinetics - ANSWER- -distributed throughout the body

, -crosses placenta

-enters breast milk

-excreted uncharged in urine


Amikacin - ANSWER- short-term IM or IV use


Gentamicin - ANSWER- ophthalmic, topical, IV, intrathecal, impregnated beads on surgical

wire, and liposomal injection


Kanamycin - ANSWER- parenteral forms


Neomycin - ANSWER- topical and oral


Streptomycin - ANSWER- IM


Carbapenems Contraindications & Cautions - ANSWER- known allergy to any carbanems or

beta lactams

Seizure disorders

Meningitis

Lactation

Caution in pregnancy


Carbapenems - ANSWER- used only in severe infections


Weight benefit and effects

Test urine function

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