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Advanced Pharmacology Final Exam Review| questions and answers(recommended by professors)

Name: Advanced Pharmacology Final Exam Review| questions and answers(recommended by professors)
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Advanced Pharmacology Final Exam Review| questions and answers(recommended by professors)Advanced Pharmacology Final Exam Review| questions and answers(recommended by professors) Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? - correct answers-To inhibit the development of tolerance What does a low level of thyroid-stimulating hormone indicate? - correct answers-Hyperthroidism What would be the best option to treat a newly diagnosed patient with a low TSH level with? - correct answers-Propanolol (Inderal) Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - correct answers-Aldosterone antagonist Heparin exerts its therapeutic action by what? - correct answers-Upregulating the activity of one of the body's natural anticoagulant molecules, antithrombin III What physiologic action happens when the offending drug is administered during an anaphylactic reaction. - correct answers-Mast cells liberate large doses of histamine. What are two systemic psoriasis medications? - correct answers-Photo-therapy and topical corticosteroids What is the first choice of drug therapy for the majority of patients with uncomplicated stage I hypertension? - correct answers-Thiazide diuretics What is the effect of cardiac glycosides? - correct answers-Digitalis glycosides have a negative chronotropic effect on the cardiac muscle cells. Amenorrhea is the most common side effect of which birth control medication? - correct answers-Medroxyprogesterone (Depo-Provera) What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor sites? - correct answers-Atenolol (Tenormin) What type of action does nitrates have on the body? - correct answers-Reduction in systemic venous tone. What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known coronary artery disease? - correct answers-100mg/dl or less. What is the MOA of group IV anti-dysrhythmia drugs? - correct answers-Depressing phase 4 depolarization and lengthening phases 1 and 2 repolarization. Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-establish eumetabolic state in a patient with Graves' disease? - correct answers-Anti-thyroid drugs. Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency? - correct answers-Loop diuretic. What drug should be considered as first-line Advanced Pharmacology Final Exam Review| questions and answers(recommended by professors) Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? - correct answers-To inhibit the development of tolerance What does a low level of thyroid-stimulating hormone indicate? - correct answers-Hyperthroidism What would be the best option to treat a newly diagnosed patient with a low TSH level with? - correct answers-Propanolol (Inderal) Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - correct answers-Aldosterone antagonist Heparin exerts its therapeutic action by what? - correct answers-Upregulating the activity of one of the body's natural anticoagulant molecules, antithrombin III What physiologic action happens when the offending drug is administered during an anaphylactic reaction. - correct answers-Mast cells liberate large doses of histamine. What are two systemic psoriasis medications? - correct answers-Photo-therapy and topical corticosteroids What is the first choice of drug therapy for the majority of patients with uncomplicated stage I hypertension? - correct answers-Thiazide diuretics What is the effect of cardiac glycosides? - correct answers-Digitalis glycosides have a negative chronotropic effect on the cardiac muscle cells. Amenorrhea is the most common side effect of which birth control medication? - correct answers-Medroxyprogesterone (Depo-Provera) What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor sites? - correct answers-Atenolol (Tenormin) What type of action does nitrates have on the body? - correct answers-Reduction in systemic venous tone. What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known coronary artery disease? - correct answers-100mg/dl or less. What is the MOA of group IV anti-dysrhythmia drugs? - correct answers-Depressing phase 4 depolarization and lengthening phases 1 and 2 repolarization. Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-establish eumetabolic state in a patient with Graves' disease? - correct answers-Anti-thyroid drugs. Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency? - correct answers-Loop diuretic. What drug should be considered as first-line

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advanced pharmacology final exam review questions

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Advanced Pharmacology Final Exam Rev
lb lb lb lb

iew| questions and answers(recommend
lb lb lb

ed by professors)
lb lb

Whylbarelbnitrate-freelbperiodslbeverylb24lbhourslbnecessarylbforlbthelbpatientlbonlbnitroglycerinlbtherapy?lb-
lbcorrectlbanswers-Tolbinhibitlbthelbdevelopmentlboflbtolerance

Whatlbdoeslbalblowlblevellboflbthyroid-stimulatinglbhormonelbindicate?lb-lbcorrectlbanswers-Hyperthroidism

WhatlbwouldlbbelbthelbbestlboptionlbtolbtreatlbalbnewlylbdiagnosedlbpatientlbwithlbalblowlbTSHlblevellbwith?lb-
lbcorrectlbanswers-Propanolollb(Inderal)

Spironoaldactonelb(Aldactone)lbhaslbwhatlbmechanismlboflbactionlb(MOA)?lb-lbcorrectlbanswers-
Aldosteronelbantagonist

Heparinlbexertslbitslbtherapeuticlbactionlbbylbwhat?lb-lbcorrectlbanswers-
Upregulatinglbthelbactivitylboflbonelboflbthelbbody'slbnaturallbanticoagulantlbmolecules,lbantithrombinlbIII

Whatlbphysiologiclbactionlbhappenslbwhenlbthelboffendinglbdruglbislbadministeredlbduringlbanlbanaphylacticlbrea
ction.lb-lbcorrectlbanswers-Mastlbcellslbliberatelblargelbdoseslboflbhistamine.

Whatlbarelbtwolbsystemiclbpsoriasislbmedications?lb-lbcorrectlbanswers-Photo-
therapylbandlbtopicallbcorticosteroids

WhatlbislbthelbfirstlbchoicelboflbdruglbtherapylbforlbthelbmajoritylboflbpatientslbwithlbuncomplicatedlbstagelbIlbhype
rtension?lb-lbcorrectlbanswers-Thiazidelbdiuretics

Whatlbislbthelbeffectlboflbcardiaclbglycosides?lb-lbcorrectlbanswers-
Digitalislbglycosideslbhavelbalbnegativelbchronotropiclbeffectlbonlbthelbcardiaclbmusclelbcells.

Amenorrhealbislbthelbmostlbcommonlbsidelbeffectlboflbwhichlbbirthlbcontrollbmedication?lb-lbcorrectlbanswers-
Medroxyprogesteronelb(Depo-Provera)

Whatlbislbanlbanti-hypertensivelbagentlbwhichlbcompeteslbwithlbepinephrinelbforlbavailablelbbeta-
receptorlbsites?lb-lbcorrectlbanswers-Atenolollb(Tenormin)

Whatlbtypelboflbactionlbdoeslbnitrateslbhavelbonlbthelbbody?lb-lbcorrectlbanswers-
Reductionlbinlbsystemiclbvenouslbtone.

Whatlbislbthelbrecommendedlblevellboflblow-
densitylblipoproteinlbcholesterollb(LDL)lbforlbpatientslbwithlbknownlbcoronarylbarterylbdisease?lb-
lbcorrectlbanswers-100mg/dllborlbless.

WhatlbislbthelbMOAlboflbgrouplbIVlbanti-dysrhythmialbdrugs?lb-lbcorrectlbanswers-
Depressinglbphaselb4lbdepolarizationlbandlblengtheninglbphaseslb1lbandlb2lbrepolarization.

, Whichlbdruglbtherapylbshouldlbbelbusedlbtolblowerlbthelbserumlbconcentrationlboflbthyroidlbhormoneslbandlbre-
establishlbeumetaboliclbstatelbinlbalbpatientlbwithlbGraves'lbdisease?lb-lbcorrectlbanswers-Anti-thyroidlbdrugs.

WhichlbtypelboflbdiureticlbwouldlbbelbusedlbforlbalbstagelbIlbhypertensionlbinlbalbpatientlbwithlbrenallbinsufficiency?
lb-lbcorrectlbanswers-Looplbdiuretic.

Whatlbdruglbshouldlbbelbconsideredlbaslbfirst-
linelbtherapylbforlbalbclientlbwithlbhypertensionlbandlbheartlbfailure?lb-lbcorrectlbanswers-Enalaprillb(Vasotec)

Whichlbdruglbislbconsideredlbsafelbforlbhypertensionlbtreatmentlbduringlbpregnancy?lb-lbcorrectlbanswers-
Methyldopalb(Aldomet)

Whatlbdruglbwilllbreducelbafterloadlbbecauselbitlbislbanlbalpha-adrenergiclbblocker?lb-lbcorrectlbanswers-
Prazosinlb(Minipress)

Whatlbislbanlbexpectedlbeffectlboflbthelbuselboflbalbbeta-adrenergiclbblockerlbtolbcontrollbangina?lb-
lbcorrectlbanswers-Reducedlbforcelboflbcardiaclbcontraction.

WhatlbsidelbeffectlbshouldlbbelbmonitoredlbcloselylbinlbthelbelderlylbwhenlbtakinglbMetforminlb(Glucophage)lbforl
btypelb2lbdiabetes?lb-lbcorrectlbanswers-Lacticlbacidosis.

Whatlbislbthelbprimarylbrolelboflbcytochromelbp-450lbinlbthelbliver?lb-lbcorrectlbanswers-
Deactivatelbandlbdetoxifylbmedicationslbandlbotherlbsubstances.

WhatlbislbalbcomponentlboflbVitaminlbK-dependentlbclottinglbfactors?lb-lbcorrectlbanswers-Prothrombin

HowlbarelbIVlbmorphinelbandlbnitroglycerinlbbeneficiallbinlbacutelbheartlbfailure?lb-lbcorrectlbanswers-
Decreaselbpreload.

Whatlbislbthelbpurposelboflbadministeringlbalbvasodilatinglbdruglbtolbalbpatientlbinlbheartlbfailure?lb-
lbcorrectlbanswers-Decreaselbafterload.

WhatlbarelbsomelbcontrindicationslbforlbHMG-colbAlbreductaselbinhibitorslb(statins)?lb-lbcorrectlbanswers-
Theylbcauselbmyopathies,lbespeciallylbatlbhigherlbdoseslborlbinlbcombinationlbwithlbcertainlbdrugs.lbTheylbshouldl
bneverlbbelbusedlbinlbpatientslbtakinglbWarfarinlb(Coumadin).

WhichlbdruglbcanlbreducelbserumlbLDLlbthelbmostlbinlbpatientslbwithlbhyperlipidemia?lb-lbcorrectlbanswers-
Lovastatinlb(Mevacor)

WhichlbdruglbislbcontrindicatedlbinlbalbpatientlbwithlbMyasthenalbGravis?lb-lbcorrectlbanswers-
Procainamidelb(Pronestyl).

Whatlbactionlbislbmostlbeffectivelbinlbdecreasinglbthelbrisklboflbhyperkalemialbassociatedlbwithlbthelbstartlboflbangi
otensin-convertinglbenzymelbinhibitorlb(ACEI)lbtherapy?lb-lbcorrectlbanswers-
Makinglbsurelbthatlbthelbpatientlbislbwelllbhydrated.

Whatlbfactorlbinfluenceslbplasmalbproteinlbdruglbbindinglbandlbdistributionlboflbthatlbdrug?lb-lbcorrectlbanswers-
Thelbamountlboflbalbuminlbavailablelbinlbthelbbloodlbstream.

Whatlbdoeslbthelbhalf-lifelboflbalbmedicationlbdetermine?lb-lbcorrectlbanswers-
Howlboftenlbthelbdruglbislbtolbbelbadministered.

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