Latest Test Bank For Lehninger Principles Of Biochemistry, 8th Edition 2024 By David L. Nelson
Lehninger Principles of Biochemistry Ch 1-6 Questions and Correct Answers
All for this textbook (3)
Written for
University of Surrey (UNIS)
Unknown
Analytical And Clinical Biochemistry
All documents for this subject (10)
Seller
Follow
Lakuscholars
Content preview
Diabetes Mellitus Type 1
02 January 2021 17:59
High glucose and beta-hydroxy butyrate levels, low pH are result of Diabetic ketoacidosis caused by
type one diabetes mellitus.
Classification of diabetes -terminology
Aretaeus the Cappadocians
Physician of 2nd to 3rd century AD
Born in Cappadocia
"the patients never stop making water…the flow is incessant, as if from the opening of
aqueducts….many parts of the flesh pass out along with the urine"
'Mellitus' added by Thomas Wills
Physician of 17th century AD
"the urine from people with diabetes is……wonderfully sweet as if permeated with honey or sugar"
Type 1 diabetes mellitus - Insulin-dependent diabetes mellitus (IDDM)
Type 2 diabetes mellitus - Non-insulin-dependent diabetes mellitus (NIDDM)
Diabetes- uncontrolled water excreted as urine from the body
Glucosuria diabetes (sweet) - diabetes mellitus
Non-glucosuria diabetes (not sweet) - diabetes insipidus
Characteristics of major types of diabetes mellitus
In individuals with type 1 diabetes mellitus the level of insulin is reduced within the pancreas and
there are less insulin hormones present in the islets of Langerhans, which under normal condition at
very high percent.
The younger the onset of diabetes, the fewer the insulin containing islets remain.
Urine protein/creatinine (UPCR) ratio is a widely used initial method to estimate daily protein
excretion in urine.
Genetic predisposing variants and environmental influences interact
Disease-associated variants in immune function and beta cell development genes occur more
predominantly in early onset type 1 diabetes and are associate with more aggressive insulitis than
other genetic variants.
After the onset of diabetes, there are more variants that are associated with type 1 diabetes,
whereas, if type 1 diabetes arrives late, the genes that are associated with the disease will be much
Diabetes Mellitus Page 1
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Lakuscholars. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.21. You're not tied to anything after your purchase.