HEME FINAL EXAM WITH ALL QUESTIONS
AND 100% VERIFIED ANSWERS
Which of the following is normally seen in the peripheral blood smear of
an adult? - ANSWER Neutrophilic band
What can be said about the appearance or morphology of all the stem
cells in the bone marrow? - ANSWER b. They all have a very similar
appearance
What does the term "erythroid hyperplasia" mean? - ANSWER
Increased red cell production
What does the term "intramedullary hemolysis" mean? - ANSWER Red
cells being broken inside the bone marrow
How do blood cells get from the bone marrow into peripheral circulation?
- ANSWER Squeezing through slits between endothelial cells
Which of the following cells do NOT normally have one or more nucleoli?
- ANSWER Myelocyte
What causes the cells to pass through the aperture to be counted on
automated cell counters? - ANSWER Vacuum
As immature red cells mature, what can be said about the nuclear
chromatin clumping? - ANSWER It gets more clumped.
Which of the following is true of immature red cells? - ANSWER There
are not granules in immature red cells
How soon must the blood smear be made after a lavender top has been
collected to prevent artifacts? - ANSWER 5 hours
,As the erythroid cells mature in the bone marrow, the color of the
cytoplasm on Wright's stain: - ANSWER Changes from 'royal blue to
pink as hemoglobin is produced.
Contains dark nuclear chromatin with very distinct chromatin-
parachromatin separation, averages 3 nuclear lobes. - ANSWER
Segmented neutro
Contains fully developed nuclear chromatin; huge irregular dark blue
staining granules which obscure the nucleus. - ANSWER Basophil
Smallest cell; deep purple staining nucleus (round or oval): little nuclear
chromatin-parachromatin separation: blue cytoplasm. - ANSWER
Lymphocyte
Largest cell: large amounts of bluish-gray cytoplasm; loosely woven.
"lacelike" nucleus: often has vacuoles. - ANSWER Monocyte
What is the normal fat to cell ratio in a healthy young adult bone
marrow? - ANSWER 50:50
Hematopoiesis in a site OTHER than the bone marrow in an adult is
called: - ANSWER Extramedullary
Which of the following cells has the ability to self-renew? - ANSWER
Pluripotential stem cell
Which of the following organs is primarily responsible for destroying
senescent (old) red cells? - ANSWER Spleen
Arrange the cells and cytokines in correct order of maturation starting
with the least mature - ANSWER Pluripotential stem cell
Multipotential stem cell
CFU-GEMM
Myeloblast
Basophil
, What ability must red cells possess to escape the macrophages in the
spleen? - ANSWER Deform their shape
Which of the following is the BEST way to distinguish a myeloblast from
a lymphocyte? - ANSWER Nuclear chromatin clumping
A cell has a horse-shoe shaped nucleus and fine granules. Which of the
following is the BEST way to distinguish this cell as a monocyte versus a
band? - ANSWER Color of cytoplasm
The patient has many large cells in the blood which have high N/C ratio,
multiple nucleoli, no granules and fine nuclear chromatin. The patient's
clinical condition most likely is: - ANSWER Leukemia
A The patient has 3% of cells with huge red-orange granules and a
segmented nucleus. The patient's clinical condition is most likely: -
ANSWER Normal
A At what stage of development can a neutrophil be distinguished from a
basophil? - ANSWER Myelocyte
Which of following cells can be found in the blood of a normal healthy
adult? - ANSWER Reticulocyte (Diffusely basophillc erythrocyte)
A A patient has 5 orthochromic normoblasts (metarubricytes) in the
peripheral blood per 100 white blood cells. Which of the following can be
said regarding the normalcy of this finding? - ANSWER a. Normal for a
newborn infant; abnormal for an adult
The patient has leukocytosis with a left shift. What is the most likely
associated clinical condition? - ANSWER Bacterial infection
What is the main function of lymph nodes? - ANSWER Immunity
Which of the following is NOT a hematopoletic growth factor? -
ANSWER Adventitial factor
AND 100% VERIFIED ANSWERS
Which of the following is normally seen in the peripheral blood smear of
an adult? - ANSWER Neutrophilic band
What can be said about the appearance or morphology of all the stem
cells in the bone marrow? - ANSWER b. They all have a very similar
appearance
What does the term "erythroid hyperplasia" mean? - ANSWER
Increased red cell production
What does the term "intramedullary hemolysis" mean? - ANSWER Red
cells being broken inside the bone marrow
How do blood cells get from the bone marrow into peripheral circulation?
- ANSWER Squeezing through slits between endothelial cells
Which of the following cells do NOT normally have one or more nucleoli?
- ANSWER Myelocyte
What causes the cells to pass through the aperture to be counted on
automated cell counters? - ANSWER Vacuum
As immature red cells mature, what can be said about the nuclear
chromatin clumping? - ANSWER It gets more clumped.
Which of the following is true of immature red cells? - ANSWER There
are not granules in immature red cells
How soon must the blood smear be made after a lavender top has been
collected to prevent artifacts? - ANSWER 5 hours
,As the erythroid cells mature in the bone marrow, the color of the
cytoplasm on Wright's stain: - ANSWER Changes from 'royal blue to
pink as hemoglobin is produced.
Contains dark nuclear chromatin with very distinct chromatin-
parachromatin separation, averages 3 nuclear lobes. - ANSWER
Segmented neutro
Contains fully developed nuclear chromatin; huge irregular dark blue
staining granules which obscure the nucleus. - ANSWER Basophil
Smallest cell; deep purple staining nucleus (round or oval): little nuclear
chromatin-parachromatin separation: blue cytoplasm. - ANSWER
Lymphocyte
Largest cell: large amounts of bluish-gray cytoplasm; loosely woven.
"lacelike" nucleus: often has vacuoles. - ANSWER Monocyte
What is the normal fat to cell ratio in a healthy young adult bone
marrow? - ANSWER 50:50
Hematopoiesis in a site OTHER than the bone marrow in an adult is
called: - ANSWER Extramedullary
Which of the following cells has the ability to self-renew? - ANSWER
Pluripotential stem cell
Which of the following organs is primarily responsible for destroying
senescent (old) red cells? - ANSWER Spleen
Arrange the cells and cytokines in correct order of maturation starting
with the least mature - ANSWER Pluripotential stem cell
Multipotential stem cell
CFU-GEMM
Myeloblast
Basophil
, What ability must red cells possess to escape the macrophages in the
spleen? - ANSWER Deform their shape
Which of the following is the BEST way to distinguish a myeloblast from
a lymphocyte? - ANSWER Nuclear chromatin clumping
A cell has a horse-shoe shaped nucleus and fine granules. Which of the
following is the BEST way to distinguish this cell as a monocyte versus a
band? - ANSWER Color of cytoplasm
The patient has many large cells in the blood which have high N/C ratio,
multiple nucleoli, no granules and fine nuclear chromatin. The patient's
clinical condition most likely is: - ANSWER Leukemia
A The patient has 3% of cells with huge red-orange granules and a
segmented nucleus. The patient's clinical condition is most likely: -
ANSWER Normal
A At what stage of development can a neutrophil be distinguished from a
basophil? - ANSWER Myelocyte
Which of following cells can be found in the blood of a normal healthy
adult? - ANSWER Reticulocyte (Diffusely basophillc erythrocyte)
A A patient has 5 orthochromic normoblasts (metarubricytes) in the
peripheral blood per 100 white blood cells. Which of the following can be
said regarding the normalcy of this finding? - ANSWER a. Normal for a
newborn infant; abnormal for an adult
The patient has leukocytosis with a left shift. What is the most likely
associated clinical condition? - ANSWER Bacterial infection
What is the main function of lymph nodes? - ANSWER Immunity
Which of the following is NOT a hematopoletic growth factor? -
ANSWER Adventitial factor
