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ALL NBME review Exam Questions and Answers
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ALL NBME review Exam Questions and Answers
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ALL NBME review Exam Questions andAnswers
TRYPTASE iiMAST iiCELL
TRYPSIN iiPANCREAS ii- iiAnswers ii-Tryptase iiMast iiCell iiSpecific
marker iimast iicell iiactivation
type ii1 iihypersensitvity iiuriticaria
angioedema iivisceral iiedema iihypotension
Length iiConstant ii= iiMyelination ii- iiAnswers ii-Demylination iiin iiMS iiDecreases iiLength
iiConstant
A-Delta iiFibers
thin iimyelinated iifibers ii- iiAnswers ii-Thin iiMyelinated iiNerve iiFibers
Detect iiTemperature ii+ iiNociceptive
GTO ii1B
extrafusal iifibers ii- iiAnswers ii-Series iiConnection ii
Increase iiTension iitransmit iivia iiGTO
1b iicontact iiinhibitory iiinterneuron
Prevents iidamage iito iiMSK
Red iifacial iilesion iipersist iiinto iiadulthood
different iifrom iistrawberry iihemangioma iiwill iiregress ii- iiAnswers ii-Sturge iiWeber
iiDisease
Leptomeningeal iiAngiomatosis
CT: iiHemispheric iiAtrophy iidue iito iiVenous iiInfarction iiTram-Track iiCalcification
Chromosome ii10 ii- iiAnswers ii-C-Cell iiCarcinoma
BACLOFEN
Skeletal iiMuscle iiRelaxant
Side iiEffects: ii
Hypotension
Drowsy iiFatigue ii- iiAnswers ii-inhibits iimono iipoly iisynaptic iireflex ii@ iispinal iicord
,Treat: ii
1) iiMS iiSpasticity ii
2) iiSpinal iiCord iiSpasticity
3) iiTrigeminal iiNeuralgia
Solar iiElastosis
Actinic iiKeratoses ii- iiAnswers ii-Elastin iiin iiDermis- iiDamaged
Neutrophil iiin iiS. iiCorneum= iiMunro iiAbscesses
Psoriasis ii- iiAnswers ii-Neutrophil iiStratum iiCorneum
Dermis: iiimagine iineutrophil ii+ iieosinophils
dermatitis iiherpetiformis ii- iiAnswers ii-
- iiGranulomas ii: iisecrete iiIFN-Y
- iiIFN-Y: iiactivates iimacrophage
-macrophage: iiincrease ii1-a iihydroxylase
-1-a iihydroxylase: iiincrease iiactive iivitamin iiD ii=)
High iiCalcium iiLow iiPTH ii- iiAnswers ii-GRANULOMATOUS iiDISEASES ii+ iiCALCIUM
iiLEVELS
1) iiSarcoidosis
2) iiHodgkin iiLymphoma
1) iiMetastasis iiCancer iiCells
2) iiCytokines ii
3) iiChemokines
4) iiPTHrP ii- iiAnswers ii-HyperCalcemia iiCauses
Necrotizing iiFascitis ii- iiAnswers ii-1. iiFever iiHypotension
2. iiPain iiout iiof iiProportion
-Strep iiPyogenes
-Staph iiAureus
- iiC. iiPerfringens
Tyrosine iiKinase
1) iiInsulin
2) iiIGF-1
3) iiCytokines ii- iiAnswers ii-Insulin iiIGF-1 iiCytokines
Hydrophobic iiAA iispan iitransmembrane: iivaline iialanine iimethionine iiisoleucine
,INSULIN
Tyrosine iiPhosphorylates iiIRS
IRS iiPhosphoryl: ii2 iiPathways ii- iiAnswers ii-IRS iiundergoes ii1) iior iipathway ii2)
1) ii
Tyrosine iiAutoPhosphorylates
MAP-phosphorylates iiRAS
Goal: iiCell iiGrowth iiDNA iiSynthesis
2) ii
Multiple iiSignals
PI3K iiPathway: iiGLUT4 iiTransport=)
Goal: iiglucose iitransport, iilipid, iiprotein iisynthesis
Histidinemia ii- iiAnswers ii-A.R. iiHistidase iiDeficiency
Psychomotor iiRetardation
Emotional iiDisturbance
AA iiwith ii3 iititrate iiprotons ii- iiAnswers ii-Histidine
Arginine
Lysine
Aspartic iiAcid
Glutamic iiAcid
Tyrosine
1) iiCleaves iiPhospholipid ii
2) iiMessenger iiof iiIP3 iiand iiDAG ii- iiAnswers ii-1) iiLipid iicleaved iiby iiPLC
2) iiSecondary iiMsgr iiis iiPKC iiof iiboth
1) iiPFK-1 ii
2) iiF iiBisPhosphatase ii1
3) iiFastest iiSugar iiDigested ii- iiAnswers ii-1) iiGlycogenesis iiUsed
2) iiGluconeogenesis iiused
3) iiFructose iiis iifastest! iibypasses iithe iiPFK-1 iirate iilimiting iistep
Aberrant iiSerine iiThreonine iiPhosphorylation ii- iiAnswers ii-INSULIN iiRESISTANCE
, Serine iiThreonine iiPhosphorylated iinormal iiinsulin iireceptor iibefore iiTyrosine iiKinase
iidoes
Abberant iiPhosphorylation:
1) iiTNF-a ii2) iiCatecholamine ii
3) iiGlucocorticoids ii4) iiGlucagon
PDGF ii- iiAnswers ii-PDGF iiSecreted iiBy:
1) iiadherent iiplatelets
2) iiendothelial iicells
3) iimacrophages
-promotes iismooth iimuscle iicell iimigration iifrom iimedia iito iiintima
-subsequent iiproliferation
Thickening iiand iiCollagen iiDeposition ii- iiAnswers ii-Smooth iiMuscle iiCells: iiVCAM-1
TRIMETHAPHAN ii- iiAnswers ii-Mecamylamine
Hexamethonium ii
All iiGanglion iiBlockers!
Classic iicomplement iipathway iibegins iiwith iiwhich iicomponents? ii- iiAnswers ii-Antigen-
antibody iicomplexes ii+ iiC1
Lectin iicomplement iipathways iibegins iiwith iiwhich iicomponents? ii- iiAnswers ii-Microbial
iisurfaces ii(e.g., iimannose) ii+ iimannose-binding iiligand ii(forms iiC1-like iicomplex) ii+ iiC4
What iiconvertase iiis iishared iiby iithe iilectin iiand iiclassical iipathways? ii- iiAnswers ii-
C4b2b ii(aka iiC3 iiconvertase)
What iiinitiates iithe iialternative iipathway ii- iiAnswers ii-Spontaneous iiand iimicrobial
iisurfaces ii+ iiC3
What iiis iithe iiunique iiconvertase iiused iiby iithe iialternative iipathway? ii- iiAnswers ii-
C3bBb ii(aka iiC3 iiconvertase)
Deficiency iithat iiincreases iisusceptibility iito iitype iiIII iihypersensitivity ii- iiAnswers ii-C3
iideficiency ii(this iiis iibecause iiC3*a* ii[not iiC3b] iiaids iiin iithe iiclearance iiof iiimmune
iicomplexes)
Oprelvekin ii- iiAnswers ii-IL-11 iiRecombinant iicytokine
Indicatd iifor iithrombocytopenias ii(as iiis iithrombopoietin)
Identify iitarget iiof iifollowing:
Alemtuzumab
Bevacizumab
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