NBME Practice MCB Questions 1-200 with Correct Answers [Updated 2024] Grade A+
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Course
NBME
Institution
NBME
NBME Practice MCB Questions 1-200 with Correct
Answers [Updated 2024] Grade A+
A 2 year old girl who is exposed to the sun has progressive development of dryness of the skin, excessive
freckling, and keratoses. Skin fibroblasts cultured from this child are most likely to be defective in which
o...
A 28 year old man is diagnosed with advanced testicular cancer. Combination chemotherapy is being
considered. Cisplatin is included in the regimen because of its effect on which of the following?
DNA
A study is conducted of breast cancer cell invasion of surrounding tissues and metastasis. Two breast
cancer cell lines, in the presence and absence of macrophages are analyzed. The macrophages are found
to secrete a protein that is essential for invasion and metastasis. This protein is most likely which of the
following?
Metalloproteinases (MMPS)
An investigator is studying the effect of paclitaxel on the growth of breast cancer cells. The investigator
observes that the drug binds to microtubules. This binding will interfere with the completion of which of
the following stages of the cell cycle?
M phase
A 3 year old boy is brought to the physician because of episodes of sunburn after brief sun exposure
during the past 18 months. Typically, the sunburn persisted for more than 2 weeks. A 12 year old cousin
has basal cell carinoma. Physical examination shows numerous freckles and erythamatous, scaly, rough
macules in sun exposed areas. Anaylsis of cultered skin fibroblasts shows a tenfold increased sensitivity
to ultraviolet radiation compared with standard human fibroblasts. which of the following DNA lesions is
the most likely cause of the findings in this patient?
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