Exam (elaborations)
USMLE STEP 2 CK INTERNAL MEDICINE
- Course
- Institution
USMLE STEP 2 CK INTERNAL MEDICINE
[Show more]
Content preview
USMLE STEP 2 CK INTERNAL MEDICINELeukemoid reaction - Answers-Patient has leukocyte count >50k, high LAP score, more
metamyelocytes than myelocytes
Chronic myeloid leukemia - Answers-Patient has leukocyte count often >100k, low LAP
score, fewer metamyelocytes than myelocytes, absolute basophilia
Cyclosporine - Answers-Drug that inhibits transcription of IL-2, causes nephrotoxicity,
htn, neurotoxicity, glucose intolerance, infection, malignancy, gingival hypertrophy and
hirsutism
Tacrolimus - Answers-Drug that inhibits transcription of IL-2 but does not cause
hirsutism or gum hypertrophy
Mycophenolate - Answers-Drug that is a reversible inhibitor of inosine monophosphate
dehydrogenase (rate-limiting enzyme in de novo purine synthesis), causes bone
marrow suppression
Vertebral osteomyelitis - Answers-IV drug user presents with tenderness to gentle
percussion over spinous process, labs show thrombocytosis
Acute pericarditis - Answers-Patient presents with sharp, pleuritic chest pain that is
relieved by leaning forward
Diabetic ketoacidosis - Answers-Patient with DM presents with hyperventilation, glucose
250-500, bicarb <18, elevated anion gap, serum osmolality <320
Hyperosmolar hyperglycemic state - Answers-Patient with DM presents with altered
mentation, glucose >600, bicarb >18, normal anion gap, serum osmolality >320
Hyperglycemia, ketonemia and anion gap metabolic acidosis - Answers-DKA Triad
Protein C deficiency - Answers-Underlying hereditary cause of transient
hypercoagulable state in first few days of warfarin therapy, leading to warfarin-induced
skin necrosis
Autoantibodies to platelet factor 4 - Answers-Genetic susceptibility to heparin-induced
thrombocytopenia
Cholesterol embolism - Answers-Patient with history of comorbid conditions presents
with livedo reticularis, Hollenhorst plaques (eyes), eosinophilia, renal injury after cardiac
catheterization
Statin - Answers-Drug used in therapy for patient with estimated 10-year ASCVD risk
>=7.5%
, Triglycerides - Answers-Lipid level reduced by use of fish oil
Niacin - Answers-Drug that is effective in raising HDL and has a modest effect of
lowering VLDL and LDL
Aortic regurgitation - Answers-Murmur in which patient presents with mild exertional
SOB and "pounding" of heart, aware of heartbeat while lying on L side, widened pulse
pressure (inc. systolic and dec. diastolic BP), water hammer pulse
Aortic stenosis - Answers-Murmur in which patient has pulsus parvus et tardus (small
amplitude and delayed upstroke)
Pyramidal tract disease - Answers-Condition detected by pronator drift test (patient has
outstretched arms with palms up and eyes closed, affected arm drifts downward and
pronates)
Romberg test - Answers-Test for proprioception in which patients are observed for
unsteadiness as they stand with feet together, arms to sides and eyes closed
Leser-Trelat sign (indicates occult internal malignancy) - Answers-Sudden onset of
multiple seborrhetic keratoses
CNS lymphoma - Answers-HIV+ patient presents with EBV DNA in CSF, MRI shows a
weakly ring-enhancing mass that is solitary and periventricular
Toxoplasmosis - Answers-MRI of HIV+ patient shows multiple, ring-enhancing, spherical
lesions in the basal ganglia
Squamous cell carcinoma - Answers-Former smoker presents with anorexia,
constipation, inc. thirst, easy fatigability, hypercalcemia d/t PTHrP , hilar mass on CXR
Acute respiratory distress syndrome - Answers-Paitent presents with dec. lung
compliance, pulmonary htn, hypoxemia with PaO2/FiO2 ratio =<300 mmHg
Central retinal artery occlusion - Answers-Patien presents with loss of monocular vision,
treated with ocular massage and high flow oxygen
Subacute thyroiditis (de Quervain) - Answers-Patient has prominent fever, hyperthyroid
symptoms, painful/tender goiter
Disseminated histoplasmosis - Answers-HIV+ patient presents with weight loss,
pulmonary symptoms (cough, dyspnea), mucocutaneous lesions, HSM, pancytopenia,
transaminitis, inc. LDH and ferritin
Relative risk - Answers-Measure of association used in cohort studies
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller GEEKA. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
83225 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now