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PTC Gene & Bitter Taste Test| Questions with complete Solution| Verified Answers
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PTC Gene & Bitter Taste Test| Questions with complete Solution| Verified Answers
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PTC Gene & Bitter Taste Test|Questions with complete Solution|
Verified Answers
PAV and AVI are found most - ANSWER frequently in human populations (>90% of haplotypes
are AVI or PAV)
The other haplotypes (AAI, AAV, PVI) are associated with - ANSWER intermediate tasting ability
Theoretically, the known SNPs could combine to form dozens of distinct haplotypes, but so far -
ANSWER only a few haplotypes have been observed
The 3 most common SNPs could combine to form - ANSWER 8 distinct haplotypes, but only
5 haplotypes have been observed
-REVIEW
PTC alleles are named for the - ANSWER variant amino acids they encode
PAV is - ANSWER dominant allele and most common allele found in human populations
-REVIEW THE ALLELE PART (don't understand)
, Phenotypes for this is - ANSWER taste or not taste
PTC is a - ANSWER transmembrane protein
It appears that all variant TC alleles encode proteins that have a structure similar to the -
ANSWER PAV protein, even though they have lost some or all of their function in PTC
tasting
ex. AVI variant appears capable of inserting into the membrane and recognizing the PTC ligand
-loss of tasting ability seems to be due to the loss of signal transduction in the cell (signal
transduction refers to molecular signals within a cells that result in some cellular change)
-REVIEW
The fact that all nontaster alleles still encode - ANSWER full-length protein is quite different
from what we usually see in recessive alleles at other loci
-much more common to see a recessive allele encoding no protein, or a much altered version
of the wild-type protein
"Ala" = - ANSWER alanine
PVI - ANSWER very uncommon
AAV - ANSWER fairly uncommon
AAI - ANSWER 3rd most common
AVI and PAV - ANSWER common
A combination of 3 SNPs along a particular gene give the ability to - ANSWER taste PTC "taster"
or gives the lack of this ability
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