©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Biochem murphy exam 3 questions with
correct answers
Which of the following describes the flow of genetic information as stated in the central dogma of
molecular biology? - Ans:✔✔-DNA to RNA to Protein
Which of the following statements about insulin is not true? - Ans:✔✔-Insulin inhibits gluconeogenesis
via an allosteric effect on PEP carboxykinase
Which of the following statements about hormones are correct? - Ans:✔✔-1, 2, and 4 are correct
Which of these is the second of the three stages of cell signaling? - Ans:✔✔-transduction
Under which conditions are the lac structural genes expressed most efficiently? - Ans:✔✔-No glucose,
high lactose
Which of the following best describes the role of EF-Tu (elongation factor Tu) in elongation of protein
synthesis? - Ans:✔✔-It is involved in the correct binding of amino acyl tRNA to the A site of the ribosome
The DNA "backbone" is composed of - Ans:✔✔-A phosphodiester bond between 3' and 5' hydroxyl
groups of adjacent deoxyribose residues
Page 1/5
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Posttranslational modifications include all except - Ans:✔✔-disulfide bond formation
The process of translation is extremely accurate (1 mistake in 10,000) due to - Ans:✔✔-answers B and C
are correct (B: codon/anti-codon interactions. C: amino-acyl tRNA synthetases)
How many hydrogen bonds exist between this DNA strand and its complimentary strand?
TCCAAG - Ans:✔✔-15
Eukaryotic DNA is packaged very differently than bacterial DNA. Which of the following statements is
true of eukaryotic DNA packaging? - Ans:✔✔-It is packaged with special proteins known as histones.
Which of the following statements about the ubiquitination of proteins are true? - Ans:✔✔-Only
statements 1, 2, and 4 are correct.
A researcher will do which of the following to elucidate how a known receptor mediated, polar protein
molecule signals through the cell ultimately changing transcription of genes. Pick the best choice. -
Ans:✔✔-Run a transcriptome array to determine all the changes in every gene level in treated vs
untreated cells.
The classic experiment that demonstrated that radioactively labeled viral DNA transforms bacterial cells
was performed by - Ans:✔✔-Hershey and Chase
Why would siRNA be preferred over a chemical inhibitor that targets the same molecule? - Ans:✔✔-Off
targets of chemical inhibition may occur where siRNA is specific to a desired mRNA.
Page 2/5
FIRST PUBLISH OCTOBER 2024
Biochem murphy exam 3 questions with
correct answers
Which of the following describes the flow of genetic information as stated in the central dogma of
molecular biology? - Ans:✔✔-DNA to RNA to Protein
Which of the following statements about insulin is not true? - Ans:✔✔-Insulin inhibits gluconeogenesis
via an allosteric effect on PEP carboxykinase
Which of the following statements about hormones are correct? - Ans:✔✔-1, 2, and 4 are correct
Which of these is the second of the three stages of cell signaling? - Ans:✔✔-transduction
Under which conditions are the lac structural genes expressed most efficiently? - Ans:✔✔-No glucose,
high lactose
Which of the following best describes the role of EF-Tu (elongation factor Tu) in elongation of protein
synthesis? - Ans:✔✔-It is involved in the correct binding of amino acyl tRNA to the A site of the ribosome
The DNA "backbone" is composed of - Ans:✔✔-A phosphodiester bond between 3' and 5' hydroxyl
groups of adjacent deoxyribose residues
Page 1/5
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Posttranslational modifications include all except - Ans:✔✔-disulfide bond formation
The process of translation is extremely accurate (1 mistake in 10,000) due to - Ans:✔✔-answers B and C
are correct (B: codon/anti-codon interactions. C: amino-acyl tRNA synthetases)
How many hydrogen bonds exist between this DNA strand and its complimentary strand?
TCCAAG - Ans:✔✔-15
Eukaryotic DNA is packaged very differently than bacterial DNA. Which of the following statements is
true of eukaryotic DNA packaging? - Ans:✔✔-It is packaged with special proteins known as histones.
Which of the following statements about the ubiquitination of proteins are true? - Ans:✔✔-Only
statements 1, 2, and 4 are correct.
A researcher will do which of the following to elucidate how a known receptor mediated, polar protein
molecule signals through the cell ultimately changing transcription of genes. Pick the best choice. -
Ans:✔✔-Run a transcriptome array to determine all the changes in every gene level in treated vs
untreated cells.
The classic experiment that demonstrated that radioactively labeled viral DNA transforms bacterial cells
was performed by - Ans:✔✔-Hershey and Chase
Why would siRNA be preferred over a chemical inhibitor that targets the same molecule? - Ans:✔✔-Off
targets of chemical inhibition may occur where siRNA is specific to a desired mRNA.
Page 2/5
