BIOL 301 Exam 1 Practice Questions and
Answers
What can distinguish between RNA and DNA? - Ans:-Presence of 2' OH on RNA
A nucleosome is composed of how many total histone molecules? - Ans:-8
In terms of MNase digestion, a chromatosome protects ___ base pairs, while a nucelosome protects ___
b...
Who used DNase, RNase, and protease to prove that DNA was the "transforming agent" of
Strepococcus? - Ans:✔✔-Avery, MacLeod, and McCarty
Who collected data on base rations (purines equal pyrimidines)? - Ans:✔✔-Chargaff
Who built the first accurate model for the structure of DNA? - Ans:✔✔-Watson and Crick
Who transformed Type IIR bacteria into Type IIS bacteria in mice? - Ans:✔✔-Griffith
Who used 32P and 35S to show the genetic information in bacteriophage T2? - Ans:✔✔-Hershey and
Chase
What are the purines? - Ans:✔✔-Adenine and Guanine
What are the pyrimidines? - Ans:✔✔-Cytosine and Thymine
Who performed denaturation mapping of phage DNA to demonstrate bidirectional replication? -
Ans:✔✔-Schnos and Inman
What enzyme in prokaryotes lays down the RNA primers on the lagging strand? - Ans:✔✔-DNA primase
Polymerases that "back up" to remove bases that were incorporated incorrectly are utilizing what
activity? - Ans:✔✔-3' to 5' exonuclease activity
Which enzyme extends the DNA at chromosomal ends? - Ans:✔✔-Telomerase
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