Content Focus Content Highlights Learning Activities
OBSTRUCTION FROM CONDITIONS IN THE WALL OF Identify the major
THE LUMEN obstructions
Asthma resulting from
alterations in the
Acute Bronchitis
wall of the lumen.
Chronic Bronchitis
OBSTRUCTION RELATED TO LOSS OF LUNG Discuss the
PARENCHYMA manifestations,
Emphysema symptoms and
diagnosis of
emphysema.
OBSTRUCTION OF THE AIRWAY LUMEN Identify the different
Bronchiectasis obstructions of the
airway lumen.
Bronchiolitis
Cystic Fibrosis
Acute Tracheobronchial Obstruction
Epiglottitis
Croup Syndrome
This study source was downloaded by 100000891982236 from CourseHero.com on 10-23-2024 06:00:17 GMT -05:00
Over time, the continued inflammation and abnormal chemical environment of asthma cause physical
changes in the bronchi and bronchioles that are known as airway remodeling.
Compare the normal bronchiole with the bronchiole from a person who has chronic asthma. Note the
increased amount of mucus in the bronchial lumen in asthma. Look for these changes that contribute to
accumulation of mucus:
Increased number of goblet cells in the mucosa
Hypertrophy of submucosal mucus glands
Note these additional aspects of airway remodeling in asthma:
Thickened basement membrane
Mucosal layer contains many inflammatory cells
Airway smooth muscle layer is thicker due to hypertrophy and hyperplasia
Discuss how airway remodeling affects respiratory function.
This study source was downloaded by 100000891982236 from CourseHero.com on 10-23-2024 06:00:17 GMT -05:00
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