VBSC 211 Chapter 2&3 Exam Answered And Graded 2024/25
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Course
VBSC 211
Institution
VBSC 211
What are the three immediate responses to infection? - Correct Answer (1) Immediate response of the Innate Immune System
(2) Components of the innate immune system are mobilized in response to infection
(3) Adaptive Immune Response
How does the barrier function work? - Correct Answer Mecha...
VBSC 211 Chapter 2&3 Exam Answered And Graded
2024/25
What are the three immediate responses to infection? - Correct Answer (1) Immediate
response of the Innate Immune System
(2) Components of the innate immune system are mobilized in response to infection
(3) Adaptive Immune Response
How does the barrier function work? - Correct Answer Mechanical: tight junctions of
epithelial cells keep things out
Chemical: enzymes (lysozyme) in tears and saliva
Microbiological: commensal bacteria take up all the space in the gut so there isn't room
for bad bacteria
How do pathogens damage tissues? - Correct Answer (1) Infect a cell and kill it
(2) Bacteria make exotoxins (part of the bacteria that can induce an inflammatory
response)
What are the three functions of the immediate innate immune response? - Correct
Answer (1) Identify the pathogen (marking it for destruction)
(2) Induce inflammation
(3) Kill the pathogens or keep them from growing (forming granulomas)
How does complement fight infection? - Correct Answer (1) Covalently binds to the
surface of the pathogen marking it for destruction
(2) Create pores in membranes causing pathogens to die (lesser used)
What are the three ways complement can be activated? - Correct Answer (1)
Alternative Pathway
(2) Classical Pathway
(3) Lectin Pathway
What mechanisms prevent complement from marking human cells? - Correct Answer
DAF & MCP: gpi linked, induces dissociation factor of C3b and allows Bb to be cleaved
which results in an inhibitor (C3bi)
Factor H
Factor I
What mechanism keeps complement from being inactivated by pathogens? - Correct
Answer Factor P (makes a little shell around the complement mechanism)
How are pathogens marked with complement destroyed? - Correct Answer
Phagocytosis (macrophages eat them)
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