HEM.ONC exam 3 AHN 554 Study Guide
Lab findings associate with IDA - Ans:-decreased hg
decreased to normal MCV
increased RDW or normal
increased ferritin
decreased transferring saturation
decreased iron
HYPOchromic, MICROcytic
Normal RBC levels - Ans:-Males 4.7-6.1 million/mm3
Females 4.2-...
What is TIBC (Total Iron Binding Capacity) - Ans:✔✔-Measurement of transferrin iron binding capability
(1/3 of transferrin is typically bound with iron)
normal transferrin levels - Ans:✔✔-Measured as a saturation ratio- Iron/TIBC
normal 20-50%
Transferrin level in IDA? - Ans:✔✔-less than 15%
What is sideroblastic anemia? - Ans:✔✔--Hypochromic microocytic anemia (can be normocytic or
macrocytic)→ small size, lack of color
-Hereditary anemia characterized by inefficient iron uptake resulting in dysfunctional hemoglobin
synthesis
-Not able to process iron, doesn't get stored/reused
- Can be caused from chemo/radiation
- reversible if caused by alcohol, medications, thiamine deficiency and copper deficiency
What is aplastic anemia? - Ans:✔✔-- rare condition caused by failure of blood cell production due to
destruction of bone marrow cells
What can cause aplastic anemia? - Ans:✔✔-unknown but suspected from benzene, HIV, EBV,
sulfonamides, methimazole/PTU, SLE
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