N115 TAKE HOME MIDTERM EXAM STUDY QUESTIONS AND ANSWERS
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Course
N115
Institution
N115
N115 TAKE HOME MIDTERM EXAM
STUDY QUESTIONS AND ANSWERS
Which one of the following is not a major feature of an ideal drug?
a. demonstrated effectiveness
b. covalent interaction with receptor
c. receptor selectivity
d. no adverse effects - Ans:-ANS: B
Variability of drug response in an indiv...
Which of the following is true regarding a drug that binds extensively to plasma proteins?
a. will likely have a large volume of distribution [Vd]
b. will be readily eliminated by the kidney
c. is unlikely to affect the bioavailability of other drugs
d. only unbound drug is available for distribution - Ans:✔✔-ANS: D
Acidification of the urine by high doses of Vitamin C [ascorbic acid] may result in:
a. better elimination of meperidine [Demerol], a basic drug, due to ion trapping
b. better elimination of aspirin, an acidic drug, due to ion trapping
c. altered concentration gradient and faster absorption of meperidine [Demerol], a basic drug
d. altered concentration gradient and faster absorption of aspirin, an acidic drug - Ans:✔✔-ANS: A
Which of the following does NOT influence the degree to which a drug moves by passive diffusion?
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