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Chapter 01: Cellular Biology ....................................................................................................................................... 4
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Chapter 02: Genes and Genetic Diseases ................................................................................................................... 13
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Chapter 03: Epigenetics and Disease ......................................................................................................................... 23
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U SN T ai ai O .................................................................................................................................................................... 23
Chapter 04: Altered Cellular and Tissue Biology ...................................................................................................... 27
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Huether & McCance: Understanding Pathophysiology, 6th Edition .......................................................................... 39
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Chapter 06: Innate Immunity: Inflammation and Wound Healing Huether & McCance: Understanding Pathophysi
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ology, 6th Edition....................................................................................................................................................... 48
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Chapter 07: Adaptive Immunity................................................................................................................................. 60
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Chapter 08: Infection and Defects in Mechanisms of Defense Huether & McCance: Understanding Pathophysiolog
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y, 6th Edition .............................................................................................................................................................. 66
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SINGTB.COM ............................................................................................................................................................... 74
Chapter 09: Stress and Disease .................................................................................................................................. 76
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Chapter 10: Biology, Clinical Manifestations, and Treatment of Cancer Huether & McCance: Understanding Patho
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physiology, 6th Edition .............................................................................................................................................. 81
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Chapter 11: Cancer Epidemiology ............................................................................................................................. 87
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Chapter 12: Cancer in Children ................................................................................................................................. 91
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Chapter 13: Structure and Function of theNeurologic System Huether & McCance: Understanding Pathophysiolog
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y, 6th Edition ............................................................................................................................................................. 94
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Chapter 14: Pain, Temperature, Sleep, and Sensory Function Huether & McCance: Understanding Pathophysiolog
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y, 6th Edition ............................................................................................................................................................ 105
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Chapter 15: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function............................... 116
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Chapter 16: Disorders of theCentral and Peripheral Nervous Systems and theNeuromuscular Junction ................. 126
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Chapter 17: Alterations of Neurologic Function in Children Huether & McCance: Understanding Pathophysiology,
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6th Edition .............................................................................................................................................................. 138
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Chapter 18: Mechanisms of Hormonal Regulation .................................................................................................. 147
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Chapter 19: Alterations of Hormonal Regulation..................................................................................................... 156
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Chapter 20: Structure and Function of the Hematologic System Huether & McCance: Understanding Pathophysiol
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ogy, 6th Edition ........................................................................................................................................................ 169
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Chapter 21: Alterations of Hematologic Function ................................................................................................... 176
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INGTB.COM ............................................................................................................................................................... 177
Chapter 22: Alterations of Hematologic Function in Children Huether & McCance: Understanding Pathophysiolog
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y, 6th Edition ........................................................................................................................................................... 192
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Chapter 23: Structure and Function of the Cardiovascular and Lymphatic Systems Huether & McCance: Understan
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ding Pathophysiology, 6th Edition ........................................................................................................................... 200
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Chapter 24: Alterations of Cardiovascular Function ................................................................................................ 210
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U SN T ai ai O .................................................................................................................................................................. 210
SINGTB.COM ............................................................................................................................................................. 223
U SN T ai ai O .................................................................................................................................................................. 226
U SN T ai ai O .................................................................................................................................................................. 228
Chapter 25: Alterations of Cardiovascular Function in Children Huether & McCance: Understanding Pathophysiol
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ogy, 6th Edition ........................................................................................................................................................ 229
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SNT
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Chapter 26: Structure and Function of the Pulmonary System Huether & McCance: Understanding Pathophysiolog
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y, 6th Edition ............................................................................................................................................................ 236
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Chapter 27: Alterations of Pulmonary Function ...................................................................................................... 245
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, Chapter 28: Alterations of Pulmonary Function in Children Huether & McCance: Understanding Pathophysiology,
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6th Edition ............................................................................................................................................................... 257
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Chapter 29: Structure and Function of the Renal and Urologic Systems Huether & McCance: Understanding Patho
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physiology, 6th Edition ........................................................................................................................................... 265
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Chapter 30: Alterations of Renal and Urinary Tract Function Huether & McCance: Understanding Pathophysiolog
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y, 6th Edition ........................................................................................................................................................... 273
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Chapter 31: Alterations of Renal and Urinary Tract Function in Children Huether & McCance: Understanding Pat
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hophysiology, 6th Edition ....................................................................................................................................... 280
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Chapter 32: Structure and Function of the Reproductive Systems Huether & McCance: Understanding Pathophysio
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logy, 6th Edition....................................................................................................................................................... 286
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Chapter 33: Alterations of the Female Reproductive System Huether & McCance: Understanding Pathophysiology,
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6th Edition ............................................................................................................................................................... 295
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Chapter 34: Alterations of the Male Reproductive System ...................................................................................... 300
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Chapter 35: Structure and Function of the Digestive System Huether & McCance: Understanding Pathophysiology,
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6th Edition .............................................................................................................................................................. 305
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Chapter 36: Alterations of Digestive Function ......................................................................................................... 312
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Chapter 37: Alterations of Digestive Function in Children ...................................................................................... 325
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Chapter 38: Structure and Function of the Musculoskeletal System Huether & McCance: Understanding Pathophys
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iology, 6th Edition.................................................................................................................................................... 334
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U SN T
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Chapter 39: Alterations of Musculoskeletal Function .............................................................................................. 342
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Chapter 40: Alterations of Musculoskeletal Function in Children Huether & McCance: Understanding Pathophysio
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logy, 6th Edition....................................................................................................................................................... 352
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U SN T
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Chapter 41: Structure, Function, and Disorders of the Integument Huether & McCance: Understanding Pathophysi
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ology, 6th Edition..................................................................................................................................................... 357
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Chapter 42: Alterations of the Integument in Children ............................................................................................ 366
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, Chapter 01: Cellular Biology
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Huether & McCance: Understanding Pathophysiology, 6th Edition
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MULTIPLE CHOICE ai
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
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with histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
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b. A nucleus ai
c. Free-floating nuclear material ai ai
d. No organelles ai
ANS: B a i
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its nuc
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leus; thus, the nucleus should be observed. A single circular chromosome called a prokaryote
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contains free-floating nuclear material but has no organelles.
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REF: p. 2 ai ai
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
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describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
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a. Metabolic absorption ai
b. Communication
c. Secretion
d. Respiration
ANS: D ai
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability invol
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ves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and secretion al
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lows for the synthesizing of new substances.
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REF: p. 2 ai ai
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
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the genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm ai
ANS: C ai
The region of the cell that contains genetic material, including a large amount of ribonucleic ac
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id, most of the DNA, and DNA-
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binding proteins, is the nucleolus, which is located within the cell’s nucleus. Mitochondria is a
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ssociated with cellular respiration, while ribosomes are involved with protein manufacturing.
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Cytoplasm is a fluid filling that is a component of the cell.
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REF: p. 2 ai ai
