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MCB10 Final Exam Study Guide- Test Questions Questions and Correct Answers the Latest Update and Recommended Version
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CQ-If a cell loses the function of both alleles of a tumor suppressor gene, what do you think would happen? increased cell division CQ- Phenotypes of human behavior such as autism, addiction, or eating disorders are..(______ traits) multifactorial traits CQ- Clinical depression can be tre...

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MCB10 Final Exam Study Guide- Test
Questions Questions and Correct
Answers the Latest Update and
Recommended Version
CQ-If a cell loses the function of both alleles of a tumor suppressor gene, what do you think

would happen?

✓ increased cell division


CQ- Phenotypes of human behavior such as autism, addiction, or eating disorders

are..(______ traits)

✓ multifactorial traits


CQ- Clinical depression can be treated with antidepressant drugs like Prozac, Paxil or Zoloft.

How do they work?

✓ Decreasing the uptake of serotonin into the presynaptic neuron


CQ- Which of the following would you predict to lead to a genetic predisposition to "thrill

seeking" behavior?

✓ -environmental factors in the womb leading to increased DNA methylation of the gene
encoding the D4 dopamine receptor in the developing fetus
✓ -an individual that is heterozygous for a nonsense mutation in the gene encoding the D2
dopamine receptor protein


CQ-What would happen if the cell cycle proceeded normally, except that physical division of

the cell did not occur?



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✓ a large cell with multiple nuclei would result


CQ- Rb is a tumor suppressor gene that when non-functional leads to retinoblastoma, a cancer

of the eye. You are volunteering at a clinic where they diagnose and treat children with

retinoblastoma. If you see a patient who has retinoblastoma in BOTH EYES it is most likely that

the child...

✓ inherited a mutant allele of Rb, and acquired mutations in the other allele of Rb in both
eyes


CQ- What is the normal Her2 Gene?

✓ a proto-oncogene


CQ-Which is the best description of what Herceptin is?

✓ an inhibitor of an oncogene


CQ-In a sample from a given population, the following genotypes were observed for the

gene ALPHA

60A/A ; 130 A/a ; 40 a/a

What is the allele frequency of a?

✓ 0.46


CQ- Cystic fibrosis is a recessive condition. The incidence of people who have Cystic Fibrosis in

the population is 1/20000=0.0005. What is the predicted frequency of Cystic Fibrosis

carriers in the population?




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✓ 0.043


CQ- Which of the following would NOT increase genetic diversity within a population?

✓ population bottle neck


CQ- In 1600s a shipwrecked slave ship land on the island of St. Vincent in the Caribbean.

Many of the enslaved West African individuals aboard the ship survived and joined a native

island with another populations forming a new ethnic group. they resulted from...( migration,

bottle neck, mutation, founder effect)

✓ migration


CQ- what was the mechanism of evolution that caused the lactase persistence alleles of the

LCT gene to increase in cattle-herding population over many generations?

✓ Natural selection of a heritable germline mutation that enables an individual to digest
milk


CQ-Whole genome sequencing can be used to

✓ -identify disease causing genetic mutations
✓ -identify variations in the genome that increase a persons risk for disease
✓ -identify specific mutations in a malignant cancer and lead to a personalized treatment


CQ- the GATA repeated sequence shown is a

✓ STR




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