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Pathology Exam 1 Questions and Correct Answers the Latest Update and Recommended Version

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stressors to cells? (7) 1. ischemia 2. infectious disease 3. immune rxns 4. genetic factors 5. nutritional factors 6. physical factors 7. chemical factors reversing cell injury depends on? (6) 1. type, severity and duration of injury 2. adaptive processes of the cell 3. type of...

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  • October 24, 2024
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  • 2024/2025
  • Exam (elaborations)
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Pathology Exam 1 Questions and
Correct Answers the Latest Update and
Recommended Version
stressors to cells? (7)

✓ 1. ischemia
✓ 2. infectious disease
✓ 3. immune rxns
✓ 4. genetic factors
✓ 5. nutritional factors
✓ 6. physical factors
✓ 7. chemical factors


reversing cell injury depends on? (6)

✓ 1. type, severity and duration of injury
✓ 2. adaptive processes of the cell
✓ 3. type of cell
✓ 4. level of differentiation
✓ 5. modifying factors
✓ 6. nutritional state


ischemia?

✓ lack of blood flow


these are responsible for the vast majority of infections? (2)

✓ 1. bacteria
✓ 2. viruses




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mechanisms of infectious diseases depends on ability to? (3)

✓ 1. invade and destroy cells
✓ 2. produce toxins that cause cell lysis
✓ 3. produce hypersensitivity rxns


bacteria releases these _____ that cause cell lysis?

✓ 1. endotoxins


when microorganisms or their toxins are present in blood?

✓ sepsis


Viruses kill cells by these two mechanisms?

✓ 1. direct cytopathic effect (RNA viruses)
✓ 1. indirect cytopathic effect (DNA viruses)


viruses use this mechanism to:

disturb the cellular processes of the nucleus and/or plasma membrane. Virally encoded

proteins become inserted in the membrane, altering permeability.

✓ Direct cytopathic effect (RNA viruses)


viruses use this mechanism to integrate themselves into cellular genome producing foreign

proteins?

✓ indirect cytopathic effect (DNA viruses)


mechanisms by which the immune system can lead to cell injury or death? (3)


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✓ 1. antibody attachment
✓ 2. complement activation
✓ 3. activation of imflammatory cells


normally the immune system fights against disease, but can sometimes become overzealous

and can lead to?

✓ hypersensitivity reactions


allergens have a high level of this?

✓ antibody (IgE)


genetic factors can lead to cell injury/death by these 3 means?

✓ 1. alterations of structure and number of chromosomes
✓ 2. single mutations of genes causing changes in the amount function of proteins
✓ 3. multiple gene mutations that can interact with environmental factors


how do nutritional imbalances result in cell stresses?

give example?

✓ deficiencies and excesses can cause pathology particularly during growth and
development.
✓ ex: decrease in folic acid during pregnancy can result in spina bifida.


types of physical factors that can cause stress to cells? (5)




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