©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
NURP 424 Exam 2 Study Guide with
Complete Solutions
Benzyl Peroxide - Ans:✔✔-Fight P. Ance via free radicals, and dries and removes sebum
NOT w/ Retinoids, can bleach clothes
Arythromicin and Clindamicin - Ans:✔✔-Topical form interrupts protein synthesis
NOT for Crohns, UC or coloitis (diarrhea)
Azelaic Acid - Ans:✔✔-Topical, inhibits microbial proein synthesis, decreases inflammation, bacteria on
skin, and keratinization
CAUTION w/ darker skin
Salicylic Acid - Ans:✔✔-OTC, for mild acne, anticondomal effect
Retin-A - Ans:✔✔-Topical retinoid, decrease binding of keratinization and comedones, makes them open
up
Adapoline (differin) - Ans:✔✔-Topical retinoid, decrease microcomedone formation, controls cell
differentiation, keratinization, and inflammation
Page 1/27
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Tazarotene - Ans:✔✔-Topical Retinoid, normalize differentiation and inflammation
NOT for pregnancy
Tetracycline - Ans:✔✔-Oral antibiotic for P. Acnes, comedones into pustules and papules, prevent
leasions
If contraindicatied: azithromycin, erythro or bactrim
Isotretinoin (Accuntane) - Ans:✔✔-Oral Retinoid, reduces P. acnes, reduces sebum production,
sebaceous gland size, and follicular keratinization
Skin drying, cheilitis, triglyceride decrease, increase BGL, headaches, lethargy, fgiue, GI, visual
distubances, arthralgia/myalgias
NOT for pregnancy, risk for osteoporosis, ETOH use
Topical Calcineurin Inhibbitors (Pimecrolimus & Tacrolimus) - Ans:✔✔-Steroid for atopic dermatitis, med
or short term, supress T-cells and intracellular protein binding, decreasing cytokines and mast cells
BLACK BOX w/ longterm use, CAUTION w/ preg, lact, , 2yo, immunosuppressed
Toptical Corticosteroids - Ans:✔✔-Dermatitis and psoriasis, anti-inflammatory (depress histamine and
prostaglandins), antipuritic, vasoconstrictive
increased by occlusive dressing (oitment is best for absorbtion)
Page 2/27
, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
CAUTION w/ renal fuction, pregnancy and children, skin irriation (use emollients), watch for secondary
infection
Diphenhydramine (Benadryl) - Ans:✔✔-Duppress H1 receptors, local anestheptic (nerve impulses
decreased)
CAUTION over 7days, lactation
NOT for children under 2, open skin (systemic)
Doxepin (Zonalon) - Ans:✔✔-Blocks H1 and H2, for severe puritus
CAUTION 10% + body use (drowsiness), elderly
NOT for glaucoma, urinary retention, children, lactation
Pyrethrins RTC - Ans:✔✔-Lice absorb through exoskeleton cause paralysis and death
Washing hair will deactivate its
NOT for ragweed allergy, children under 2
Permethrin - Ans:✔✔-Lice and scabies absorb throug exoskeleton x7 days
WHOLE family for scabies
NOT for children under 2mo
Page 3/27
