UConn PNB 2274 Exam 2 – Tanner Study Guide with Complete Solutions
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Course
PNB 2274
Institution
PNB 2274
UConn PNB 2274 Exam 2 – Tanner Study
Guide with Complete Solutions
Principles Electrostatic Attraction - Ans:-- charge attraction
- positively charged ions will be attracted to negatively charged ions
Principles Chemical (diffusional) Gradients - Ans:-- when a membrane is selectively permeabl...
Nernst Equation - Ans:✔✔--used for only one ion at a time
-Ex = equilibrium potential
-determines the electrical potential (voltage) at which diffusion flow of an ion one way is balanced by
electrostatic attraction in the other
What effect Equilibrium Potential ( Ex) ? - Ans:✔✔-- temperature
- Concentration of ion
Mammalian ion concentrations and Nernst Potentials - Ans:✔✔-Ek = -90, ECl = -70, ENa = +60, ECa =
+130
- these values can change based on condition
Goldman- Hodgkin- Katz Equation - Ans:✔✔--the membrane is permeable to more than 1 ion at rest
-Vm = membrane potential when net flux of all other ions together is 0
-membrane have one Vm value; it is the average Ex values for each ion
- ** permeability matters
Goldman Equation: Multiple ion Case - Ans:✔✔-Vm is somewhere between the largest Ex and smallest
Ex.
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